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Doc logic

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Doc logic

Re: flipper44 post# 59672

Monday, 04/25/2016 8:36:35 PM

Monday, April 25, 2016 8:36:35 PM

Post# of 701259
flipper44,

I agree with your conclusions. DCVax-L (primer 1) as is will be used to prime an immune response to the newest neoantigens. Then the responding T-cells will be harvested and cloned for use as an adjunct combination therapy or neoantigens will be identified, separated and those that cause the best T-cell response will be presented to DCs to create DCVax-L (primer 2). The harvested T-cells approach is being tested now and results should be known within 1 year. My understanding is that the neoantigens primed DC approach has yet to be tested.
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