NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

ae kusterer,

Maybe NWBO also feels strongly that M2 macrophages can be expected to be prevented from having a negative effect by just having enough activated DCs kept in the tumor environment long enough ( treatment spacing) with enough chemokine expression (DC selection and activation) to overwhelm tumor defenses and eliminate the tumor while at the same time building up immune memory cells (treatment duration) and creating a systemic response in up to 80 % of all solid tumor cancer types (maybe more with optimum selection and activation).