Anavex Life Sciences Corp (AVXL)

[georgejjl]

Could it be that myristic acid might be synergistic with Anavex 2-73 and/or Anavex 3-71?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450430/

DISCUSSION
Sig-1Rs have been reported to play a role in the pathogenesis of neurodegenerative disorders including AD (30, 45, 46), Parkinson’s disease (47, 48), and motor neuron disorders (49–51). The underlying molecular mechanisms of Sig-1R action remain to be totally clarified. Although we have previously demonstrated several versatile actions of Sig-1Rs as they may affect cellular survival (26–28), other mechanisms of action may exist. Here, we have identified a new action of Sig-1Rs in that Sig-1Rs regulate tau phosphorylation and axon elongation by interacting with myristic acid.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827442/

Thus, the new finding of Tsai et al. suggests that the Sig-1R apparently provides the myristic acid, by means of myristic acid “hitchhiking” on the Sig-1R that allows p35 to bind to the lipid membrane where p35 can accomplish the balanced or homeostatic activation of cdk5. This ultimately results in the regulation of normal axonal growth and maintenance.

http://reallywell.com/myristic_acid.htm

Good luck and GOD bless,

George