NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

longfellow95,

Those preexisting T-cells are already primed and targeted to antigens on the tumor cancer cells. The reasons are varied for why some patients have more or less of these pre existing primed T-cells in their system but what is known is that they have been down regulated or prevented from active engagement on cancer cells by an immunosupressive response by the cancer or tumor environment. By maintaining primed and proper chemo kine secretion active in the tumor environment and in circulation throughout the body (DCVax-L/D) cancer can be kept in check and potentially eradicated with longer term immune memory by T and B cells.