NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

Stillwell888,

No need to keep your fingers crossed because the confirmation is just a matter of time. Dr. Prins told us all how cures can be achieved by clearing the tumors. He said DC therapy plus antibody/antibodies can do this. NWBO understands how to control the tumor microenvironment and why that environment changes to being immune suppressed. They know that educated DCs can become depleted before full immune memory is achieved and or tumor mass/metasteses can be too much for a fixed injection schedule without the help of antibodies and or chemo to overcome. They know how to improve methylation in some cancer subtypes with chemo pretreatment. They know they must stop immune suppressing M2 macrophages from gaining control of tumor and metastatic environment and they have clearly seen this happen in the crossover in L, when synergies are utilized, and made the changes necessary to achieve this for their Phase 2 in Direct. What they need most now are approvals for fully automated manufacturing and rapidly expanding capacity.