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Re: hope4patients post# 57802

Monday, 03/28/2016 8:46:41 PM

Monday, March 28, 2016 8:46:41 PM

Post# of 700578
When you have a trial protocol that the entire study is designed around to achieve specific powering, I don't think you can just randomly lower enrollment and maintain the trial integrity. Maybe exwan or avii can chime in, but I think it would screw up the primary endpoint powering. I've seen several trials over enroll, but not the other way around.
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