Anavex Life Sciences Corp (AVXL)

[JB3729]

So many $billions have been spent, and wasted, on treating the symptoms of Alz.

On the other hand, A2-73 works upstream on the causes of ALZ -

Pre-clinical Study Demonstrates ANAVEX 2-73’s Ability to Preserve Mitochondrial Integrity and Block the Oxidative Stress and Cell Death that Leads to Amyloid-Beta Overproduction and Tau Hyperphosphorylation

“We provided clear evidence that the neuroprotective activity of sigma-1 receptor agonists, including the mixed muscarinic ligand/sigma-1 agonist ANAVEX 2-73, involves mitochondrial protection in AD models. Indeed, the drug efficiently protected mitochondria against amyloid-beta caused impairment of mitochondrial respiration, the key energy producing process within the cell,” said Tangui Maurice, PhD, one of the study authors and CNRS Research Director, Head of Team 2 ‘Endogenous Neuroprotection in Neurodegenerative Diseases’, at the University of Montpellier and INSERM. “Mitochondrial dysfunction and resulting oxidative stress are critical hallmarks of Alzheimer’s disease pathology and believed responsible for increased amyloid-beta production and Tau hyperphosphorylation.”
http://www.anavex.com/?news=anavex-2-73-could-prevent-alzheimers-disease-in-addition-to-modifying-and-treating-symptoms