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Re: TRUISM post# 104136

Monday, 03/07/2016 4:29:15 PM

Monday, March 07, 2016 4:29:15 PM

Post# of 278158
No present data, but there is a trend. It was only a few years ago that the only price point that we knew was $100k per kilogram. Spiber has stated that they will be a thousand times less ($100 per kilo) at commercialization and has on their website how much their costs to produce the proteins have reduced. Bolt Threads mentioned that they also will be at less than $100 per kilogram shortly after Spiber mentioned it. I just assume that the trend will continue.

Bolt Threads stated that their process is not very different than growing any other yeast and the spinning process is not to expensive anymore as well. Their transgenic yeast is "much more compatible with the secondary structure of mRNA, and handle translation of the repetitive genetic structure much more efficiently and accurately than E. coli, resulting in a higher yield of non-truncated silk protein extracts, and the potential for extracellular secretion of silk proteins, a feature not found with traditional *E. coli* chassis", so I think that they will probably end up with the cheapest product to produce assuming it drops to become cheaper than silkworms. I am still curious about the properties that they have achieved and wonder if they could rival Dragon Silk. If so, they will be a real contender once fully established.
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