NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

Rkmatters,

As someone who looks mainly for realistic and probable explanations for what is not being explained for us here, I am happy to see you have looked at AVII's theory realistically. This is a plausible explanation for putting Les's reported comments with Dr. Linda Liau's comments and creating a realistic interpretation. Good job. The one other thought I had about this is whether or not NWBO views this process as a way to give FDA reason to take an unscheduled look at data. The company of course would remain blinded during this process so they don't "know" what FDA or others will do but as flipper44 has stated, FDA may be interested enough with the data itself or with regard to CLDX to take a peak. This would also help explain the second hand comments by Les through Drum and add a necessary reason to consider the recent financing. If there were any doubt at all that the data might stay blinded to FDA, thus preventing at least an ethical quandary for FDA with regard to methylated mesenchymal GBM patients, the money would be needed for continuing the trial to regular completion or for completion with a new primary or coprimary endpoint.