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Doktornolittle

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Doktornolittle

Re: flipper44 post# 54635

Monday, 02/22/2016 12:38:38 PM

Monday, February 22, 2016 12:38:38 PM

Post# of 705558
Would it be correct to say that if they did use the 1st interim as an efficacy look beyond the DMC, that it would be an un-planned alpha-spend, and would thus lower the chance of approval both at the second interim and at full planned trial length, if such proved necessary? ...Thus it would be a gamble.
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