Friday, February 12, 2016 3:51:25 PM
How many patients (from the placebo arm or the treatment arm) that have a disease progression (PFS event) do you believe would NOT ACCEPT the crossover option, but rather drop out of the treatment part of the DCVax-L trial and decide perhaps to try something else?
My gut feeling is that nearly 100% of all patients that progress and are offered the crossover option will likely accept it. IMHO.
I believe these patients are also allowed, after they have had their PFS event, to crossover & be assured they start receiving the real vaccine, BUT ALSO (at that point in time) be allowed to seek other/additional treatment. So for example, if a patient receiving treatment at UCLA had a PFS event .... could this patient then perhaps also receive some adjunct treatment as perhaps recommended by Dr Liau & her team .... or receive some treatment combining a checkpoint inhibitor or *other*?
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