![](http://investorshub.advfn.com/images/default_ih_profile2_4848.jpg?cb=0)
Thursday, February 04, 2016 6:57:22 PM
IMO, the biggest clues come from Dr. Marnix Bosch and Dr. Linda Liau.
1. With regard to the primary end point of PFS: "Pseudo progression wreaks havoc with trials" -Dr. Bosch. It is my opinion that the 1st IA has occurred and the PFS analysis did not predict a likely chance of reaching statistical significance..
Then we have another clue from Dr. Liau.
2. With regard to the secondary end point of OS. "it seems like everyone’s living longer than we would be expecting" -Dr. Liau
If it were not for #2., this trial would likely already be dead in the water IMO. Instead everyone is left scratching their heads trying to figure out how to move forward and deal with the confounding issues surrounding OS, etc., since there seems to be a survival benefit from the treatment. Thus the 6 month delay from the 1st IA. I have a feeling the final conclusion might be to go back to the drawing board and initiate a new phase 3 trial.
With regard to Linda Powers. She is focused on trying to figure out if a certain number of investors became aware of the confidential 1st IA results before anyone else (remember the 30% intra-day drop?) and profited by shorting it down to our current levels. It would be very interesting to know if any sensitive information was communicated or "leaked" around that time. I wonder if anyone (or any group) of investors had a spontaneous "bad feeling" about the stock around that time?? Anyway, it would explain bringing on the CIA investigator specializing in the area of cyber intelligence. But like everything else, who knows..
Recent NWBO News
- Biophma Announces Exclusive In License for Dendritic Cell Technology, Sending Shares Higher • AllPennyStocks.com • 06/17/2024 04:40:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 06/04/2024 09:11:16 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 06/03/2024 09:22:55 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 05/22/2024 08:13:36 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/10/2024 09:04:57 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/01/2024 10:04:38 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 12/02/2023 01:31:35 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/16/2023 10:11:54 PM
- Epazz, Inc. (OTC Pink: EPAZ) ZenaDrone Demonstration to Defense Departments of UAE and Saudi Arabia • InvestorsHub NewsWire • 11/15/2023 12:19:31 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/09/2023 09:30:39 PM
- Epazz, Inc. (OTC Pink: EPAZ) US Navy Collaboration ZenaDrone 1000 • InvestorsHub NewsWire • 11/09/2023 01:00:34 PM
- Epazz, Inc. (OTC Pink: EPAZ) US Navy Collaboration ZenaDrone 1000 Extreme Weather Demo • InvestorsHub NewsWire • 11/07/2023 12:29:43 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/09/2023 08:36:14 PM
Last Shot Hydration Drink Announced as Official Sponsor of Red River Athletic Conference • EQLB • Jun 20, 2024 2:38 PM
ATWEC Announces Major Acquisition and Lays Out Strategic Growth Plans • ATWT • Jun 20, 2024 7:09 AM
North Bay Resources Announces Composite Assays of 0.53 and 0.44 Troy Ounces per Ton Gold in Trenches B + C at Fran Gold, British Columbia • NBRI • Jun 18, 2024 9:18 AM
VAYK Assembling New Management Team for $64 Billion Domestic Market • VAYK • Jun 18, 2024 9:00 AM
Fifty 1 Labs, Inc Announces Acquisition of Drago Knives, LLC • CAFI • Jun 18, 2024 8:45 AM
Hydromer Announces Attainment of ISO 13485 Certification • HYDI • Jun 17, 2024 9:22 AM