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Wednesday, January 20, 2016 9:18:37 PM
Staff Profile: Menghang Xia
Menghang XiaMenghang Xia, Ph.D.
Leader, Systems Toxicology, Toxicology in the 21st Century
Division of Pre-Clinical Innovation
National Center for Advancing Translational Sciences
National Institutes of Health
E-mail Menghang Xia (link sends e-mail)
Biography
Menghang Xia leads systems toxicology activities for the Toxicology in the 21st Century (Tox21) initiative at NCATS. Since joining the NIH Chemical Genomics Center, now the NCATS Chemical Genomics Center (NCGC), in 2005, she has played a key leadership role in multiple projects, including Tox21. Xia led the effort to develop and validate a battery of in vitro toxicological assays in a quantitative high-throughput screening platform. She and her colleagues have developed and screened more than 100 assays and profiled environmental chemicals on various pathways and targets, such as p53 signaling, ARE signaling and nuclear receptors.
Xia is the author or inventor for 92 peer-reviewed research articles, book chapters and patents. Her work has been highlighted in several top toxicological journals, including Chemical Research in Toxicology and Toxicological Sciences. Xia received her bachelor of medicine degree from Shanghai Medical University in China and her Ph.D. in pharmacology and toxicology from the University at Buffalo, State University of New York. She completed her postdoctoral training at the University of California, San Francisco. Before joining NCGC, Xia identified and validated several targets for drug development at Merck Research Laboratories.
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