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Re: Tony888 post# 49509

Sunday, 01/03/2016 5:17:56 PM

Sunday, January 03, 2016 5:17:56 PM

Post# of 702436
"So he/she started receiving the treatment after the screening halt. Now we have evidence that enrollment continued after the screening halt for patients already in the pipeline. Great find TC."

Maybe it was just a coincidence that they halted with the number screened and randomized matching (maybe not exactly, but close) the numbers needed for statistical signicance for 4 months PFS and 6 months PFS respectively. Rather: the number screened may have been deliberate, while the number randomized at that same point may just have happened to match the number they would need in the trial if they were to use a 6 months PFS bar. Not sure they could go back to a 6 month PFS bar anyway...
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