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Wednesday, 12/16/2015 10:45:15 AM

Wednesday, December 16, 2015 10:45:15 AM

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From $heff: $TPIV..The FDA has granted an orphan drug designation to TPIV 200 as a treatment for patients with ovarian cancer http://ow.ly/VUfy0 (OncLive)

The FDA has granted an orphan drug designation to the multi-epitope folate receptor alpha (FRa) vaccine TPIV 200 as a treatment for patients with ovarian cancer, according to a statement from the drug's developer, TapImmune.The orphan designation for TPIV 200 was based on findings from a phase I study, which were electronically published in conjunction with the 2015 ASCO Annual Meeting. In the study, treatment with the vaccine was associated with FRa-specific T-cell response that persisted beyond the completion of the study for a majority of patients. In total, FRa is expressed on nearly 90% of ovarian cancer cells. - See more at: http://www.onclive.com/web-exclusives/multi-epitope-vaccine-granted-orphan-designation-for-ovarian-cancer#sthash.07wzMG16.dpuf
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