Tuesday, December 15, 2015 6:32:56 AM
(it follows #245613 )
Zooming in the resulting chart from the eventing projections
CASE1: BAVI 13 Months MOS. Placebo 9.9 MOS
CASE2: BAVI 15 Months MOS. Placebo 9.9 MOS
CASE3: BAVI 17 Months MOS. Placebo 9.9 MOS
Now, I am unclear on how many events will be needed for the 1st Lookin. I for one would appreciate some clear insight on this matter from any knowledgeable poster.
So I drew two possible cases:
a.166 events for 1st Lookin
b.200 events for 1st Lookin
From the chart, (a) February 1st (up to March 15th? if (b)) we could have the 1st Lookin if Bavi MOS is 13 months
From the chart, (a) March 1st (up to May 1st? if (b)) we could have the 1st Lookin if Bavi MOS is 15 months (*)
From the chart, (a) March 15th (up to first week of May if (b)) we could have the 1st Lookin if Bavi MOS is 17 months (*)
(*) IMPORTANT. As I said in my previous post “Given that in all cases the distribution only shows up to 20 months, For Cases 2 & 3… beyond 19 months all patients alive are considered as survivors when they might have evented at 21 months etc… So, curves for Cases 2 & 3 are a limit on the right side for the Lookins (should take place before that)”
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