NorthWest Biotherapeutics Inc (NWBO)

[Schnauzer1]

RK,

Interesting way to look at the evolution of medical treatment for GBM. I had not considered the improvements in surgical procedures as a possible reason for some part of the claimed success in the P1/11 trials. That association is quite interesting and self proving. Well, almost self proving. Are there any studies showing the benefit of MRI enhancements, and total resection, in GBM without other treatments (I am thinking not since Stupp is the proven method, and multiple arm study for MRI usage was probably not required). Otherwise, your reference to research on this issue is quite sufficient. Thanks

I know someone who I shared a few beers with that has an inoperable GBM grade IV. Not totally sure, but think that radiation may not be an option due to location. Total reliance on Chemo. That family is in total shock. I don't think any mention of the NWBO Vax option even makes sense. The tumor load is just way to significant to even theoretically benefit from L. Your review of those associated numbers was very helpful. I have weighed that issue because if I thought there was any hope from L in that circumstance I would have raised the possibility. Even so, he has a top team and am sure they have considered every proven option. Sometimes we just have to face the inevitable. I need to remember that.