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Wednesday, 11/18/2015 1:16:37 PM

Wednesday, November 18, 2015 1:16:37 PM

Post# of 461833
"BTW; since Phase 2A Part A had such excellent results in non steady state AND non-optimized dosage, it makes sense that part of what they are testing for in the remaining Phase 2/3 is Population Pharmacokinetics/Pharmacodynamics so that they can in fact determine ideal dosage. This could very well increase the efficacy we have seen. As they state in their PR, one of the reasons to do so is to enter Phase 3 with optimal dosing to reduce/eliminate dosing as a cause of Phase 3 failure. Clearly the FDA is guiding them in how best to do so."

Marky YMB
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