NorthWest Biotherapeutics Inc (NWBO)

[Schnauzer1]

DonoE, I am no expert on these matters. But it does not make sense to me to give up a home court advantage! Assuming this stuff works, when you reach PFS point why would you discount the spread by improving the control. If you buy the argument that game over at PFS point, then explain why anyone would bother switching control to L at that point as it offers no benefit. Sounds like a lot of circular reasoning. I don't know that the spread between control and treatment will be substantial. Nor does anyone else. It's a bet. Just seems reckless! I have to discount my investment accordingly! Secondly, I don't know to what extent the FDA approves the protocol of a trial. Obviously this is not an SPA where they do. As I read the disclaimers of NWBO there is one for failure due to their lack of experience in designing trials!