Anavex Life Sciences Corp (AVXL)

[wildcard235]

The corrupt Martin Shkreli...

I usually post on Yahoo, but that message board is refusing to take my posts or even my votes on comments again, and I want to get this off my chest. (I posted earlier here about the trial results because it was too long for the YMB and I thought some folks here might like to read it.)

Disclaimer: The following comments represent my opinion about Martin Shkreli and a recent comment of his about Anavex.

I am writing about the corrupt character Martin Shkreli, the infamous person who recently bought a drug and raised the price over 5,000%), because he tweeted this about Anavex: “I shorted $AVXL - i do not believe the drug *can* work given its PK and receptor pharmacology profile.”

So he admits he has a vested interest in driving the price down and then attacks us. However, the best attack he could come up with is to try to cast doubts on our pharmacokinetic and receptor pharmacology profiles! That is idiotic, apparently meant to influence ignorant people who don’t understand what he’s talking about.

A pharmacokinetic profile basically measures whether or not a drug is being absorbed and getting to the part of the body where it is needed. A2-73 has been proven to accomplish those goals. A receptor pharmacology profile is proven or disproven by preclinical and clinical trials, not by the expressed opinion of a scurrilous twit with ulterior motives. A2-73 is a sigma-1 receptor agonist, and there are over 100 peer-reviewed scientific papers showing or indicating effectiveness in neuronal processes related to Alzheimer’s and related diseases. I’ll rely on that science over Shkreli’s dishonest claims. Our own phase 2a trial results so far indicate that our receptor profile may be more effective than anything else on the market or in development.

If Scumeli truly does not believe A2-73 can work he is an idiot. If he does not believe it, he is a liar.