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Friday, 10/30/2015 12:52:47 PM

Friday, October 30, 2015 12:52:47 PM

Post# of 463141
ANAVEX 2-73 for Epilepsy

ANAVEX 2-73 exhibited dose-dependent significant anti-convulsive action by providing almost complete to complete protection from tonic seizures in three established seizure models.

"In maximum electroshock (MES)-induced convulsions, 30 mg/kg ANAVEX 2-73 provided 90% protection. In pentylenetetrazol (PTZ)-induced convulsions, the same dose provided 85% protection. In a semicarbazide (SCZ) model, the same dose was able to delay the tonic seizures from 56.9 seconds to 99.2 seconds. In (PTZ)-induced convulsions, 60 mg/kg ANAVEX 2-73 had a long-lasting effect with 100 % seizure protection after both 4 and 6 hours, respectively."
http://www.anavex.com/?news=anavex-releases-promising-full-preclinical-epilepsy-data-at-antiepileptic-drug-trials-xiii-conference

"Currently, there are no drugs available that truly control epilepsy or prevent epileptogenesis, a process that causes long-term tissue and cell damage as well as biochemical and physiological alterations to the brain. These alterations cause seizures and are linked with the progressive deterioration or death of the body’s nerve cells,” said Dr. Kontzalis, Chief Executive Officer for ANAVEX. “In addition, the drugs to treat epilepsy that are on the market today are often associated with cognitive, psychotic and memory problems. As such, we believe that novel drugs like ANAVEX 2-73 and ANAVEX 19-144, which have anti-epileptogenic, neuroprotective and anti-amnesic properties, are certain to have a major impact on the anti-epileptic drug market around the world."
http://www.anavex.com/?news=anavex-advances-drug-candidates-for-treatment-of-epilepsy

Dr French has been hard at-work and it is about to get explosive!

Yes, it's still just beginning. The gurus are just starting to spout:

"And second, on a smaller, more personal note, Anavex is exactly the sort of company I had in mind when I launched my premium service, Penny Stock Millionaire, last year.

Fortune favors the bold,

Alex Koyfman"

I concur, "Anavex is exactly the sort of company I had in mind when I started trading stocks again, last year."

More to follow...

U.S. Prov. Pat. App. No.62/065,833
“A19-144, A2-73 and Certain Anticholinesterase Inhibitor Compositions and Method for Anti-Seizure Therapy”
Unpublished


They have one year from this filing to file a corresponding nonprovisional application.
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