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Wednesday, 10/14/2015 7:54:45 AM

Wednesday, October 14, 2015 7:54:45 AM

Post# of 462258
A doctor (epileptologist - spelling?) posted this on another board. Sounds like he knows quite a bit about the science -

With all due respect - hope and greed are not the only thing this company and its investors have.

I don't think you have done your due diligence regarding the effectiveness of sigma 1 receptor agonists. If you read the preclinical data and delve deep into the mouse models of alzheimers - with the sigma 1 knock out mice vs. the mice on anavex 2-73 --- there are objective measures of tau protein markers that prove that the the drug works; that sigma 1 receptor agonists actually modify the pathologic process whereby brains get clogged with amyloid proteins/etc.

Sigma 1 receptor agonist - like anavex 2-73 actually reverses the amyloid aggregation and reverses the pathologic process.

Considering that mammals have similar neurophysiology (at the microscopic level - all nerves, synapses work the same) - the implication is obvious to the scientists amongst us (not you).........sigma 1 receptor agonists - like anavex 2-73 - is the first out of many previous failed drugs - to stop and reverse the pathophysiological process that can lead to neurodegenerative diseases - like Alzheimers.

Is this not a fundamental in your view?
Are the results from the prelim data - phase 2a in the summer a sham?

What the original poster was trying to convey - you can do all the TA you want - but if you ignore the science, you are doing so at your own risk. Objective Data and science ALWAYS beats subjective technical analysis in the longterm......PERIOD

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