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Re: rafunrafun post# 61228

Monday, 10/12/2015 9:47:52 AM

Monday, October 12, 2015 9:47:52 AM

Post# of 426573
rafunrafun

Agreed that it's a drug from different class. But it's not the first class that have failed. GSKs darapladib (LpPLA2 inhibitor) failed. Zetia+Lipitor combo failed (over lipitor alone).

My point is, we discuss here a lot about stopping at interim due to high efficacy, and never talk of a stop due to lack of efficacy, which is equally possible. Like the fibrates and niacin failed to show benefit in CVOTs.

If V succeeds, it will be no less than a miracle.
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