NorthWest Biotherapeutics Inc (NWBO)

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Extremely important patent issued on October 1, 2015.

Application number: 20150273033
Type: Application
Filed: Nov 05, 2014
Issued: Oct 01, 2015
Inventors: Marnix Leo Bosch (Clyde Hill, WA), James Kelly Ganjel (Bethesda, MD), Linda F. Powers (Bethesda, MD), Linda M. Liau (Los Angeles, CA), Robert M. Prins (Pacific Palisades, CA)
Application Serial: 14/533,879

COMBINATIONS OF CHECKPOINT INHIBITORS AND THERAPEUTICS TO TREAT CANCER
Nov 05, 2014
The present disclosure arises at least in part from the seminal recognition that a combination treatment regimen including one or more cycles and/or doses of a checkpoint inhibitor and a therapeutic, either sequentially, in either order, or substantially simultaneously, can be more effective in treating cancer in some subjects and/or can initiate, enable, increase, enhance or prolong the activity and/or number of immune cells, or a medically beneficial response by a tumor.