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Thursday, 09/10/2015 12:52:36 PM

Thursday, September 10, 2015 12:52:36 PM

Post# of 403181
My favorite R&R slide.

Shows Mean Drug Liking on Visiual Analog Scale (VAS). Time is on horizontal axis. On the verticle axis, anything above 50 means they liked it, below 50 they disliked it. Notice the expected liking of snorted oxyIR (green). ELI-200 (blue) is actually *disliked* at the outset- see how the blue line falls below the placebos (red & yellow). For some reason, drug abusers disliked snorting it, as opposed to feeling neutral, like snorting the placebo. And ELI-200 never bumps above the placebo line, indicating the naltrexone effect is long-lasting. (I'm looking at you, alleged-ADF Targiniq, with your short half-life naloxone instead of longer half-life naltrexone.) A great data slide. Thanks Nasrat!



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