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Re: biopharm post# 230443

Sunday, 08/16/2015 8:16:41 PM

Sunday, August 16, 2015 8:16:41 PM

Post# of 345981
And why do we want Docetaxel to ellicit PS ?

I got this from post 152368-Dr.Brekken's words-
" These are ( MDSC'S )-I have to describe them as teenagers. These are cells that have not developed into their final form...They are unproductive in a lot of ways.So MDSC'S are present in tumors and they have a phenotype that drives immunosupression. However because these are teenagers, you can educate( them ).You can drive them towards a productive endpoint...However, there are ways in which we can educate these MDSC'S to differentiate into cells that are productive with respect to generating an immune response."

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