Innovation Pharmaceuticals Inc (IPIX)

[To infinity and beyond!]

Just for kicks, guys and gals, to get at how mysterious this all is, despite so much being known. Click on the Cell Death article referenced by slcimmuno and then look at figure 1, the extended version. It shows the frequency of various gene mutations for different types of cancer. For ovarian, for example, ALL of the leading mutants are p53 mutants. Look at the graph: it is amazing.

And then look at AML- p53 mutants are not even among the leaders at all. And the same is true of renal cell cancer, graph also shown

And yet- where is K's first 2/3 trial? it's for AML!!! The cancer it did so well against n the original ASCO poster, if you want to go back and look it up.

And the other trial we keep hearing about is for renal cell cancer with Beth Israel with sunitinib.

How interesting is that? Two cancers where p53 mutants are not the big players, and still Kevetrin works well against these tumors?

Pretty interesting I would say.

Ovarian cancer as a target would seem logical- but how much don't we understand?