NorthWest Biotherapeutics Inc (NWBO)

[Pyrrhonian]

Linda never lied? Didn't she say the trial was enlarged "a little bit" and then said increased by 36 patients from 312 to 348? If you don't think that's lying I'm not sure what to say.

I have no doubt most of those labeled rapid progressors were in fact rapid progressors. But it's still possible one or two weren't. And 15.3 months mOS is certainly less than Linda was going around everywhere suggesting the "sickest of the sick" were doing. All that came out of her mouth was "18 months in the sickest of the sick, who usually die in 7-10 months." She never clarified. Sure, if you happened to read the fine print of the slide you'd have seen "actual or suspected rapid progressors," and if you further had the wherewithal to figure out you were being tricked and knew what a psPD even was you'd at least know what she was saying wasn't honest. But please, don't tell me she wasn't lying. I know what a lie is.

I also know you and flipper are really impressed with these patients having had 50% growth of their lesions after 5 months, but it's just not that special to an ePD. These are not "super rapids" or whatever you want to call them. They are quickly progressing ePD who usually die from 3-15 months historically. It's a sad, sick disease. If anything this new info should make you more suspicious of how to classify the "indeterminates." But with so much confirmation bias how could you?

You stated the criteria correctly but omitted when a patient is scanned for that criteria. The fact is after 2 months either those apparent lesions grew or stayed the same or even regressed (just not more than 25%) for those labeled "indeterminates." Well, how many regressed or were stable at 2 months post baseline scan? Most of them? Who knows! These could easily all be psPD. Every single one labeled "indeterminate." If they scanned again at 6 months etc., they would have more conclusive data. They just didn't. Nothing nefarious, they were compassionate use patients after all.

So, not really sure what point you're trying to make or thought you just made. Probably all or almost all of those labeled "rapid progressors" are ePD. Probably most if not nearly all of those labeled "indeterminates" are psPD. And because they did not take additional scans we'll never know.

These information arm data are simply unsubstantiated without a concurrent control group. It doesn't matter if the ePD mOS is 20 months, neither the market nor the greater health community will credit DCVax-L with the ability to procure a survival advantage unless such data comes from a randomized trial.

Aren't you all getting tired of my repeating the same rudimentary matters? Why not just learn it already instead of fighting against it constantly. Accept the truth.