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Thursday, 04/02/2015 8:17:03 AM

Thursday, April 02, 2015 8:17:03 AM

Post# of 711574
"It is clear Mr. Feuerenstein is incapable of clean journalism. I'd say it was complete inability to understand, but he knows he is distorting facts in his column. The 20 patients in the rapid progressor arm met Rano Criteria and MacDonald criteria for that categorization. The patients in the indeterminate group did not. The patients in the DCVax-L early progressor group exceeded all prior group data efficacy results when compared to other therapies.

Regarding DCVax-L, Mr. Feuerstein also knows trial resizings are very common before phase III results come out, and they are based upon enrollment and event rate. Resizings have nothing to do with an unblinded expectation of failure. Nothing.

Mr. Feuerstein is an unabashed cheerleader for a competitor of Northwest Biotherpeutics, Celldex, which has thus far very produced modest results at best in its phase II trials in a very narrow subclass of GBM; and yet, like a giddy school child, he wants Celldex to apply for approval.

Yep, Mr. Feuerstein has a bully pulpit, but he abuses it, misleads and manipulates." -- Flip

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