Avid Bioservices Inc (CDMO)

[Protector]

pphm2long, yes but not those with 100+% SOC improvement and Fast Track.

However, they know promising Phase III trials have failed before.

Try to find one like that that failed. No so long ago it was posted that Drug that got Fast Track have never failed PIII. Now Bavituximab is one with :
A) 100+% SOC improvement, probably close to 140%
B) Stat Sig. (because of what happened with the dose switching)
C) With a Fast Track
D) Consistently safe in ALL PI/II clinical trials (not only NSCLC)
E) Consistently improving on SOC (even Pancreatic 2 weeks on poor ECOG)
F) Showed this as well with chemo/radio as immuno therapy
G) Has a better understood MOA then at start of PII's
H) Had the super results also in Breast with CR's
I) Bavituximab works is in oncology, viral and inflammation.

So yes, some drugs pass PII and then fail PIII and are often in the category that they shouldn't even start a PIII. And some should have passed the PIII but they surely didn't have all the above. Finally some stopped for financial reasons and BP continued there work.

Furthermore I can tell you, while not official, that there isn't an hair on the head of PPHM people that doubts if this trial will succeed. I agree, they can't say that on the record for legal reasons, probably not even under the forward looking cover.