Amarin Corp Plc (AMRN)

[HDGabor]

AdCom:

"The first was for the treatment of severe hypertriglyceridemia, levels of 500 or greater, where the principal concern with these folks is that you want to get their triglycerides down in an attempt to avoid acute pancreatitis."

"the division has historically approved drugs for severe hypertriglyceridemia on the premise that treating severe elevations in triglycerides would be expected to reduce the risk of acute pancreatitis. There are estimated to be approximately 3.4 million adults in the United States with severe hypertriglyceridemia."

"It's hard to imagine an event-driven pancreatitis trial for super-high triglycerides."