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Re: HDGabor post# 33380

Wednesday, 09/03/2014 12:10:16 AM

Wednesday, September 03, 2014 12:10:16 AM

Post# of 426099
HD: Thank you for your thoughts ! I must say we're
on the same page, though the time schedule is very
different. The bottom line of clinical trials that
those that are event driven,usually take longer
than everyone thinks. Time is not our ally. I am
discouraged by the 5000 enrolled patients you state with
low LDL's. That raises the bogey for efficacy to be shown
with the Power and Hazard Ratio. Lets assume we do well
and get 18% efficacy, that's the kind of number we need.
The only thing we need is a compelling P value that shows
unequivocal efficacy.
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