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Re: exwannabe post# 33364

Tuesday, 09/02/2014 7:29:30 PM

Tuesday, September 02, 2014 7:29:30 PM

Post# of 426727
Every long term study has at least one interim analysis (IA) and IA has a stopping rules. IA is not equal with stopping rule, so AMRN's stopping rule is not the 60%. It (967 events) is the "time" of interim analysis.

R-IT's DMC has a meeting on a quarterly basis and they could recommend the early stop anytime, but usually at interim analysis, just like in case of Jupiter trial, which was stopped early, after the second interim analysis with 328 events and a median follow-up of 1.9 years at the recommendation of its Independent Data and Safety Monitoring Board.
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