Amarin Corp Plc (AMRN)

[BioChica]

Reduce-It Exclusion Criteria:

Severe heart failure
Any life-threatening disease other than Cardiovascular Disease
Active severe liver disease
Hemoglobin A1c >10.0%
Poorly controlled hypertension
Planned coronary intervention (such as stent placement or heart bypass) or any non-cardiac major surgical procedure
Known familial lipoprotein lipase deficiency (Fredrickson Type I), apolipoprotein C-II deficiency, or familial dysbetalipoproteinemia (Fredrickson Type III)
Known hypersensitivity to fish oil products
History of acute or chronic pancreatitis

Patients are excluded if using the following medications:
niacin >200 mg/day or fibrates;
any omega-3 fatty acid medications ;
dietary supplements containing omega-3 fatty acids (e.g., flaxseed oil, fish oil, krill oil, or algal oil);
bile acid sequestrants