Provectus Biopharmaceuticals Inc (PVCT): http://en.m.wikipedia.org/wiki/Haybittle...

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Provectus Biopharmaceuticals Inc (PVCT)

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Re: vorlon1966 post# 6171

Saturday, 07/19/2014 11:27:33 PM

Saturday, July 19, 2014 11:27:33 PM

http://en.m.wikipedia.org/wiki/Haybittle–Peto_boundary

Here we see the rules for stoppage when the difference in efficacy is significant or not

Stoppage rules apply when the drug shows no significant difference or a large difference after a certain number of patients. Anything in between will dictate the study be run to the end.

http://m.jme.bmj.com/content/31/7/410.full

I tried to show both sides of the stoppage rule
I hope I have explained it in detail

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