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Re: rdhitchcock post# 28705

Wednesday, 06/04/2014 9:10:00 AM

Wednesday, June 04, 2014 9:10:00 AM

Post# of 426565
Let me some thought (without medical background):

- expected event rate in R-IT placebo group is 5,2% / year
- we know that the event rate was around 1% / year in Jelis (without or with low dose of statin) - 80% lower than R-IT placebo group
- it looks like that statin does not decrease AA/EPA ratio (based on the citied study it increase)
- EPA decrease AA/EPA ratio significantly

I do not say that we will see the same event rate in R-IT Vascepa arm, but I believe the group will be 'transformed' to Japanese and the eff.% could be around 40%
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