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Re: Pyrrhonian post# 10659

Monday, 05/19/2014 4:14:35 PM

Monday, May 19, 2014 4:14:35 PM

Post# of 704257
My first impression is that:

110: PFS Events

is equivalent to

72: OS Events

In that the same language is used for these 2 milestones, however, the 60%, 80% interim analysis language is not used for OS.

I think the latter was an oversight, so let me try to fill in the blanks to get the ball rolling.

OS: First Interim Analysis = 44 events.

..Second Interim Analysis = 58 events.

Of course if this is correct, it means there will be twice the number of interim analyses if the trial goes to primary and secondary endpoint completion. You can again multiply that number by 2 when you add the pseudo progression group.

Hmmm.






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