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Re: flipper44 post# 10469

Saturday, 05/17/2014 6:38:43 AM

Saturday, May 17, 2014 6:38:43 AM

Post# of 708091
It's been an interesting market response to what can only be described as positive news.
Massive volume on the day of PR (shorts covering?) then moderate to low last session.
It begs the question, what do they need to do to catch a break?
Anyone tracking the sum of all these parts must be scratching their heads as much as I am.

Anyway, in response to these last posts, some more reading re: extensive necrosis...

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770541/

(>95%) (95%-99%)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362430/

(>30%)

http://www.europeanurology.com/article/S0302-2838(09)01193-2/fulltext/tumour-necrosis-is-an-indicator-of-aggressive-biology-in-patients-with-urothelial-carcinoma-of-the-upper-urinary-tract-img-src-manager-uploads-europeanurology-com-eur-articles-s0302-2838-09-01193-2-assets-eulogo1-jpg-alt-eulogo1


(>10%)

So, a bit of a broad definition between them.
Another quote from the PR says a "high rate of tumor necrosis" - equally ambiguous.
I'm also not quite sure what they mean by "partial collapse" of the tumor mass.
The only time I've read or heard "collapse" in reference to tumors was about the individual cells themselves. Perhaps because the DCs are doing their job from the inside out (from the injection site, deep in the mass)?

Opaque descriptions aside, the news is good: There is a meaningful effect and it's measurable and attributable to the treatment.
I'm not seeing the downside, if i wasn't already in as deep as I'm comfortable with, I'd be adding.

Best of luck to all holders, but most of all to those who are or will be afflicted by this f-ing disease.





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