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Re: foxhound02 post# 9101

Monday, 04/21/2014 3:58:02 PM

Monday, April 21, 2014 3:58:02 PM

Post# of 696721
Hi Fox,

I believe I have found a couple of abstracts that report data from ongoing trials. I need to look more closely at what they are actually reporting. I only asked the question because I wasn't sure that releasing data from a trial in progress was totally banned or not at ASCO. I've not been able to follow all of the posts about this amongst the different members and I was a little confused after reading the ASCO policies.

As for the question regarding what more could I want. I'm only asking the question because as you know, if you report something unexpected and very important (a systemic response) you damn well better have the goods to back it up. Otherwise, you come off as an amateur overstating the data. Prominent MDs and PhDs will take you down hard for that. I've seen it at poster sessions and it isn't pretty. It's even worse when it happens during the QA after a talk.

My opinion is that the title is ambiguous because the data to prove a systemic response (and it takes more than tumor regression) won't be presented. The surrogate data for a systemic response will be tumor regression.

To summarize: They can say systemic in the title because it isn't directly linked to the human data and they will have the mouse data to back it up. It's my opinion; It doesn't really matter. I just wanted to put it out there for others to consider and maybe add too it. You never know what you are missing until someone shows you. I thought maybe I was missing something.......

If I'm wrong I'll probably never hear the end of it and If I'm right I'll probably never hear anything of it.
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