AMBS
Is MANF to become the "Holy Grail" of the medical community in the coming decade and beyond? Great Find Knack!! Mart Saarma has been busy spending that 500K on his research with resounding results. "MANF Is Indispensable for the Proliferation and Survival of Pancreatic ß CellsMANF Is Indispensable for the Proliferation and Survival of Pancreatic ß Cells.[color=red][/color] Additionally, we show that lack of MANF in vivo in mouse leads to chronic unfolded protein response (UPR) activation in pancreatic islets. Importantly, MANF protein enhanced ß cell proliferation in vitro and overexpression of MANF in the pancreas of diabetic mice enhanced ß cell regeneration. We demonstrate that MANF specifically promotes ß cell proliferation and survival, thereby constituting a therapeutic candidate for ß cell protection and regeneration."
Research continues to reveal the amazing healing power of MANF that bridges the species. The more research that is done, the more dramatic is the evidence. MANF is going to be revolutionary in medicine in our lifetimes it would appear! Wow, what an article!