Great timing on Covid data! Let's see another PR in the next few days!

Tried that once before when I did not like the closing price at 6.66. It did not reflect in moving the last trade amount. Someone told me it was a min of 100 shares to do that.

If a tree falls in the forest and crash sounds like "Hey world, I have a solution for dozens of the worlds most deadly hemodynamic stability related diseases in humans", does anyone on Wall Street hear?

Wow. How the F could they not PR this? I highly doubt they could come up with reasonable explanation for having no PR.

LOL. I was pushing my toddler son in a stroller on the St. Petersburg Pier when I got notification on my cell of the CE Mark approval. He is now taller than my wife and starts 7th grade in August.

I have been laying low and focusing on other stocks recently and letting my long CTSO shares ride. I also needed a break to deal with some health issues and a break from the CTSO frustration.

I have been in CRMD for a while. I caught the initial wave with the jump after the trial halt at interim review. I thought approval would be a slam dunk when the FDA said an AdCom meeting was not needed. At least after CRL it sounded like everything was good with the actual product but there were some manufacturing questions that needed to be answered before approval. Hopefully thing should work out around year end.

I also lucked out and jumped on some AVEO calls just before approval. Another one I stumbled on in these boards.

My second largest holding after CTSO is ACRX. However, It is another paradigm shifting product like CTSO. CTSO is filtration vs. drugs while ACRX is sublingual drug delivery vs. IV. I think it will find its niche in out patient surgery. Might take a while though.

The CRMD news stung a bit. I got in early so I am still up, even my March calls. Just looks like a speed bump for them. Manufacturing questions. No new trial required.

Cousin Eddie...

LOL. While I agree CTSO should be closer to $100, if you have "sure thing" triple bagger please share. If you do, why would you have any cash in CTSO?

Personally, I believed the trading here has been manipulated for many years. It has far more positives going for it than many other biotechs I am invested in, that have comparable market caps. Micro-caps can be manipulated by a couple of trading accounts and a $ amount that is probably less than a big Pharma's or Hedge Fund's monthly coffee supply bill. If you were to have the ability to manipulate a stock, under the radar of the SEC, it makes sense to let it run up then tank it. Volatility makes money if you control or have knowledge of the triggers of the volatility and trade accordingly.

The SEC just doesn't care about these micro-caps. The only thing the company can do is keep their nose to the grindstone and and hope that eventually FDA approval, partnerships and sales push the market cap high enough that the stock prices cannot be so easily manipulated. It sucks that the manipulation causes unneeded dilution when a capital needs to be raised, but that is the way the crooked system works.

Just be happy for the poison pill provision CTSO has. If they did not, I think this company would have been stolen from investors long ago.

Well, good for them on their in-vitro study.

"in-vitro: performed or taking place in a test tube, culture dish, or elsewhere outside a living organism."

Maybe in a year or two they will have a study done in lab animals and 2 years later have phase 1&2 human studies done so they can move on to a multi-year phase 3 study.

At least their CEO has the pedigree of being the ex-CEO of AEMD. Let me check their market-cap? Hmmm... 21 million? Yup, looks like he was a great captain of that ship. I'm sure there will be no pumping and dumping of the holding tanks of his new ship.

Happy Thanksgiving. Fellow Mods, feel free to delete if you feel the need. I know some other CTSO investors jumped on the CRMD wave about 2 years ago and we made some good short term gains. This is the first biotech I have been invested in that had a study halted early by the DSMB because of efficacy demonstrated at interim analysis. Now the FDA says an AdComm meeting is not needed before the PDUFA date? This is truly unusual. I know they had issues with their CRO a few years ago, but the woman they brought in to follow-up with the data collection seemed to be top-notch. Since PDUFA date is a deadline and not an announcement date, I would love to see some good 2020 news for a change. It is up 40% in 5 days with little online hype that I have been able to find, so I do not think it is a pump and dump situation. Something is up. My guess is early FDA approval, and/or partnership or Buy-Out.

I have seen that the biggest problem in investing in these micro-cap biotechs is that even with FDA approval, if they get it and try to go-it-alone towards commercialization, building out manufacturing, marketing and sales is a loooong, like years long, process. ACRX is a good example of this, but ACRX also has the hurdle of a paradigm shift. The jump from IV to sublingual pain killers, in emergency and out-patient surgery, is not a small one.

CRMD, however, is simply a swap out of an existing product for a much better one at a comparable price. The latest CRMD PR also states: "We look forward to completion of the review of the NDA and are considering all strategic options to be able to successfully bring Defencath to the U.S. market as soon as possible." In my opinion, partnering up or a buyout takes the "long" part out of the commercialization process. This could get exciting, but if it ends up with the go-it-alone route, I bet there will be a sell-off. I'm still waiting on the Crystal Ball I ordered from Amazon. This investing thing should be much easier once it arrives.

Wow. 16 treatments over 8 days. That is in line with the frequency of the often cited refractory septic shock case study.

I have a lot of dry powder right now. Tempting, but I am gun shy after nearly15 years with this company.

Still very unusual.

Trading before hours? That is not common for CTSO.

Wow. What a sad case. The poor woman probably never even got to see her child.

Thanks. She is one the mend.

Reads like a pink sheet CV-19 hype company to me, with an Aethlon Medical connection. The CEO used to be with the NFL Denver Broncos. So, at least he has that going for him over Dr. Chan's degree from Harvard Medical School at the Beth Israel Deaconess Medical Center and his MD/PhD from Yale University School

I just got a personal example that sepsis can come from many sources. A few weeks ago my wife was picking up some of the kids toys in the front yard. Reaching under a palmetto\palm, it jabbed her knuckle. Literally like a pin prick. The next day she could not bend her finger. After 10 days on antibiotics and no improvement she got an MRI and diagnosis of septic arthritis and an infection that looks to be moving up her hand. The doctor is doing surgery tomorrow to prevent it from going to full blown sepsis. It is amazing how something so minor and random could lead to a possibly life threatening condition. They are also going to culture the bacteria to identify it and pick the best next set of antibiotics.

It looks like it was removed by a site moderator rather then a board moderator. I have no idea why or if it as bot rather than a human.

When they are a multi-billion dollar company he could play a part in the movie. I never could find much info on the Russian guy who developed the polymer technology, but I beleive he or his estate still get a small cut of sales according to the filings. Then we also have the exec from an early large contract manufacturer who illegally patented some of their technology. However, to the best of my knowledge, he and his company never kept the patents current, as there would have been litigation if they tried to.

Strange. He passed away quite a long time ago and it doesn't look like much has been done at all with this trust holding in a very long time. He was a very early investor. Were these purchases or perhaps grants of some kind related to sales? I read up on him years ago. He had a very interesting life story, was an innovator and I always wondered how he stumbled on MTSB, which seem very far removed from his area of expertise.

LOL. Still never been to Canada in my life and my name is not Rob. Red Sox, TB Rays and Toronto Blue Jays are all in the same division though, so I would love to visit for series.

Even more reason for unusual trading volume. Bummer. One of my other holdings is up about 30% for the week. I hope it holds. Seems like it had a lot more pumper noise than usual, so traders may have just been working it in conjunction with the witching.

Totally fell off my radar. Usually there is more talk on the boards about it, but today was a Triple Witching Day.

Triple witching is the quarterly expiration of stock options, stock index futures, and stock index option contracts all occurring on the same day. Triple witching happens four times a year: on the third Friday of March, June, September and December.

Yes. I still think he may be our old friend Paul\Pearsby. He went quiet on Facebook. Must have had his son help him figure out the privacy settings on that platform.

Lakersback claims he only has 50 shares. Anyone else want to chip in and pay him $20 a share if he promises to leave the board forever?

For the most part, you have to already be following the company on these social media platforms to see these posts. If you are already following them, then you know their story already. However, it puts out media that those who are following them can then share with their friends\followers. Share wide, share far, share often!

Six Sepsis related posts from Cytosorbents on FB, in the last 48 hours, leading up to World Sepsis Day. I don't really use Twittter. Any uptick in posts tweets there or news on other platforms?

Raptor, don't you already live in Hawaii?

Nope. I have some 6 cent shares that are factored in as $1.50 in my cost basis.

Sadly, I honestly do not think any trained SEC eyes would spend much time on a company just above micro-cap status.

Everyone always blames the shorts for a big rapid drop. I understand that institutional investor have high tech computer programs to execute trades. If one were to decide they wanted to take a large position, legal or not, why wouldn't they walk the price way down before they started large buys to hold?

It looks just like a big flounder. A flat fish that lays on the bottom and has both eyes on one side.

Good luck to you! I grew up in MA, boating day trip distance from Marths Vineyerd, and would catch a ton of fluke there.

LOL. I did have a drink at lunch.

I have to have been in MTSB\CTSO for close to 15 years now. I do think it is a paradigm shifting novel technology. However, I'm pretty sure we were told 1.5-2 years ago that the 80 million in manufacturing capacity was adequate for 2-3 years. Now we are told it is currently adequate for 2 more years. I just don't get it. If they have the manufacturing capability in place, if they have their own sales force and partner sales forces already established around the globe already, if they have a registry and 50+ IIT that have been established for years, if they have the RECESS study wrapping up, if they have the REFRESH 2 trial advancing, if they have FDA Breakthrough designation for removal of anti-platelet drugs, etc. How can all of these irons in the fire(and i didn't list quite a few of them) only add up to a spike in sales for CV19 that will still end up leveling out to around 80 Million sales 2 years from now?

I totally believe in the technology, but I am frustrated with this forecast.

I trimmed ~5%. 2 more years to 80 Million in sales is depressing. I put it in another biotech that I think is either way under-valued and going to take off sooner than the 2 year time frame or going to be a bust.

Yes, if it is from the registry. The Cytosorb Registry is actually setup as a 3000 patient clinical trial you can find on clinicaltrials.gov.

I don't know for sure, but I always assumed they came from cases entered in the Cytosorb Registry.