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Frau Blucher
"I am an investor - although having lost so much money in this stock, maybe that's debateable"
The only way you lose, is to sell. If you are an investor, then you are an idiot for bashing your investment.
Hulk, I thought you were an investor. I guess that really isn't so. Preclinical trials must be completed before a human trial can be attempted. It is better to get the preclinical trials done, to know exactly what our product may treat. It makes good business sense to find what our limitations either are, or aren't, with a partnership that is willing to foot the bill. As for the two clinicals, that Jay spoke of earlier, he let us know that he is still working within the initially promised time frame. However, you take the positives, of this last call, and spin it to build negative sentiment in "your" investment. That is an idiotic thing to do, if you really are an investor.
Personally, I believe our management is making great strides towards getting Leronlimab back into the clinic and restoring the damage done by the previous management and clinical research company. They have negotiated our debt to give our drug a chance to prove itself and are getting peer reviewed papers out, to showcase Leronlimab's potential for the indications that were poorly executed. They have cleaned up the data and are about to settle the score with the worthless clinical research facility that screwed us in the first place.
But yet, that isn't to your liking, so you throw in with the paid bashers on this board. Good for you I hope you get what you so richly deserve.
Looks like we may have some nice surprises coming!! Great timing for this! Jay keeps moving forward.
https://www.cytodyn.com/newsroom/press-releases/detail/620/cytodyn-to-host-webcast-to-provide-company-update
"Bet you got excited to see $.15 today! LOL
Only $.14 from zero."
Nice math skills, dummy.
"What happened to your kind heart lately ..????"
Money happened. He/She is only here to make his money by promoting negative sentiment for this stock. That is the only reason he/she has been here for the last few years. Now he/she is just like the rest of the bashers. They bring nothing to the board.
Yes Sir, it's good to see that Leronlimab is back in play. It is wonderful to see us getting back on track.
As for non-investors, we really don't care about either what you think, or have to say! We never have! Non-investors are just background noise. Get ready for change.
I see that the bashers, still, have not learned how to count. You just sit tight Jazzboy, we will have news soon!
Do you know the difference between a smart person and a dumbass? A truly smart person won't brag about how smart they are. Looks like those basher types are always telling people how smart they are.
"Seems they
want to ignore real science. Why is that?"
Money and Power?!!!
Yep, just leave the non-investor idiots to themselves. Move to boards that are moderated by investors.
Yeah, they could, then, rename the board maxdfacttsgrowidiots if the investors left it to the bashers.
Good post! Thanks for that!
Dr Jay Lalezari is, and has always been, a class act. This is the best move by Cytodyn's management that I have seen. He is very genuine in his belief of the capability of Leronlimab.
From Ohm20's post elsewhere,
"Warren Averett was allowed to resign otherwise I'm sure they would have been fired for violating auditor independence.
From the 8-k -
Quote:
On September 19, 2023, CytoDyn Inc. (the "Company" received notice from the Company’s current independent registered public accounting firm, Macias Gini & O’Connell LLP (“MGO”), informing the Company that MGO declined to stand for re-election as the Company’s fiscal year 2024 registered public accounting firm. The Company’s Audit Committee had considered, but had not formally taken action regarding, a change in the Company’s independent registered public accounting firm prior to September 19, 2023."
https://assets.pcaobus.org/pcaob-dev/docs/default-source/enforcement/decisions/documents/105-2023-022-warrenaverett.pdf
https://assets.pcaobus.org/pcaob-dev/docs/default-source/enforcement/decisions/documents/105-2023-022-warrenaverett.pdf
Here is another mechanism, showing how Leronlimab can help cognitive impairment. Klotho, a kidney protein found in the blood, helps primate cognitave ability in aging primates. CCL5 is shown to down regulate Klotho production. Know what you own!
https://www.nature.com/articles/s43587-023-00441-x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922032/
You are correct!!! And, that data is for the time period that the drug was in their system!
That seems very possible!!!
CenterWatch.com/clinical-trials/listings 218732 Pro14
Pro140 in treatment experienced HIV-1 Subjects
Participants: 25
Status: (Not recruiting)
Updated on: 23rd May/2023
DETAILS:
Condition: HIV-1-infection
Treatment: Pro140
Clinical study
Identifier: NCT03902522
Sponsor: Cytodyn, Inc.....Last modified: 23 May 2023
SUMMARY:
The primary objectives of the trial are to assess the EfficacyClinical Safety and Tolerability parameters of PRO140 in combination with failing ART during the initial one-week treatment period and in combination with Optimized Background Therapy during the subsequent 24-week treatment period.
In the battle against cancer, Leronlimab will be the treatment of choice!
Great article! Thanks for posting!
"Yet all this has just been disproven by the latest research, showing the Cytokine storm is not the culprit for COVID deaths."
That is pretty funny stuff. A study of 190 patients disproves how millions have perished. Perhaps a stronger study is needed, if it is going to be quoted as a fact. Just sayin!
This is an outstanding post! Thank you, for posting and reposting Rockleo and Misiu! Respect!!!!
"Pretty old. Later COVID research has debunked this since then. Nope, Cytokine storm is not the key culprit anymore."
Please, provide vetted research that verifies this.
Excellent find! Thank you for posting!
Perhaps the FDA is working, with management, to do more than just lift the hold. Maybe there is more going on. Hopefully, we will get some great news either tomorrow or soon. Keep the faith!
GLTUA
Other dictionaries, including Webster's New World College Dictionary, The American Heritage Dictionary of the English Language and the Cambridge Dictionary all recognize irregardless as a word.Jul 7, 2020
https://www.npr.org › 2020/07/07
Regardless Of What You Think, 'Irregardless' Is A Word - NPR
"And doesn't this Hansen guy have two brothers?"
Musical family?
Maybe CYDY should partner up for ALZ.
https://www.medpagetoday.com/neurology/alzheimersdisease/103817
Positive change in under way! IMHO!
"Maybe he doesn't want to be poked 52x a year while an alternative exists now that only requires 2 injections a year?"
Hmm, I guess he missed the part about black box warnings, and kidney and liver failure.
"Hey, ya think Charlie Sheen is still using it. Laughing"
I think the answer is, unequivocally, yes he would (if he could still get it). Why wouldn't he use a treatment that takes the viral load below a measurable amount, without destroying kidney and liver function? Everything else, currently available, comes with black box warnings. The HIV population suffers a high rate of kidney and liver failure from big pharma's combination treatments.
Yep, it's going bankrupt right now!
I meant right now!
Oh wait, it's going to be bankrupt in 5, 4, 3, 2, 1!
What I meant was, it's going to be bankrupt next week!
Wait, I meant next month. Yeah, bankrupt in a month!
If I keep saying it, I'm bound to get it right, sometime!
Just showing another post, from another OTC traded stock, that had an interruption of trading, yesterday morning. CytoDyn stock was not the only stock having trading issues yesterday.
A post from IQST board, on IHub, from yesterday.
Status: Disruption
First Reported: February 6, 2023 8:30 a.m. (ET)
Last Update: February 6, 2023 8:30 a.m. (ET)
Description: ORF FIX users are unable to deliver successful transactions; additionally some TRAQS users also are experiencing issues. FINRA is troubleshooting
Thank you for posting! What an excellent interview! Cyrus exhibits his knowledge of the drug, and the mission at hand. From his references, to where the company stands, I would say that this interview took place before the holidays. It looks like he has a good plan, and the experience to implement it.
GLTUA
From yesterday:
FINRA update on problem
ORF Transactions
FEBRUARY 06, 2023
FINRA is currently experiencing an issue with ORF (Over-the-Counter Reporting Facility) transaction messages delivered via FIX. FINRA is working on a solution and will update clients as more details are known.
https://www.finra.org/filing-reporting/orf/or...=200268659
Yeah, wasn't that going to happen in 2020? LOL!
A post shared by Riztheinvestor from another board, it is too good not to share:
From Reddit
“Here’s a good read from a scientist in 2020 and why he invested in Cytodyn.
Use your own judgement.
Actually, its probably far better than most dedicated shareholders even know. If you go back and look at the 2010 clinical trials, what you find is that 162mg biweekly of leronlimab (LL) can reduce viral load by 90% after 4 weeks, 326mg biweely will reduce it by 96% and 326mg weekly for 4 weeks will reduce it by 98%. That should tell you that LL sticks to CCR5 better than any other CCR5 blocker out there. Compare that to maraviroc which requires 300mg twice daily, and that should tell you that maraviroc only sticks for around 12 hours.
That means maraviroc is throwing 600mg per day of byproducts at the liver and kidneys, which should help everyone understand why its somewhat toxic to both organs. So what we have here is a drug that binds to CCR5 incredibly well, and if there is a medial need for that, then we have solved it better than anybody else.
If you study Dr. Maddon and his reasoning behind how he created LL, you would discover that he hunted for the very best monoclonal antibody he could create. And of course, to understand that, you need to understand how mAbs are created in the first place.
To create a mAb, they inject an immunogen into a rat or other animal to elicit an immune response. This is a brilliant use of nature to solve a problem for us. If we want an antibody that fights a virus, we can study the B-leukocytes that are creating antibodies that fight that virus. By injecting human CCR5 into the rat, we get antibodies that fight human CCR5! And that's how we created B-cells that make antibodies that bind to CCR5.
Once you have a rat making antibodies, researchers extract the B-cells from the spleen and then fuse them with human cancer cells called myelomas, to create a hybridoma. These are super-antibody factories because they have the infinite reproductive powers of cancer combined with the B-cell's antibody producing capabilities. Researchers then take each of the hybridomas, put them in their own private petri dish, and then study each one to see which one is making the best antibodies.
You see, each B-cell has its own unique way of fighting the immunogen. Each might bind (attack) the immunogen's protein strands in different locations, so its up to researchers to figure out which ones are better than the others. In the case of Dr. Maddon, he specifically sought out the mAb that binded to CCR5 in exactly the same way that HIV does. And that makes perfect sense because his goal was to stop HIV from binding to CCR5. No clue where it was just serendipity or pure genius, but this yielded one extremely effective CCR5 blocker! Maybe HIV has had thousands of years to evolve and during that evolution, myriad different permutations failed to bind until one finally found a way to attach to something in human immune cells. Dunno, don't really care. What matters here is that this drug is perhaps the most effective at binding to CCR5 of anything out there.”
The next question we should have is, "how valuable is being able to block CCR5?" We already know its highly effective at treating HIV, so that's one market we could dominate. We also know that it shows incredible promise against some cancers, and that's another market we can enter and save a lot of lives. Lastly, we know that our success in modulating the immune system suggests we can do great things to help patients with autoimmune conditions: MS, Lupus, IBS, eczema, psoriasis, and many others.
I'm a scientist so I don't go around trying to explain why it hasn't been approved or acquired. Those are man-made issues that can be easily corrected. I've covered the God-made (or nature-made for those of you God-deniers) issues, as those are written in biology and physics, and not really subject to the whims of man.
Another interesting paper that indicates an immune system modulator, that reduces inflammation, might just be the ideal treatment for Alzheimer's Disease and dementia. I wish there was a safe treatment, that can cross the blood brain barrier, and control the chemokine damage and inflation. Know what you own! This is the miracle drug! It just needs to be properly managed, to get it to the people that need it.
https://link.springer.com/article/10.1007/s12031-022-02047-1
Alzheimer's might be an autoimmune disease? It looks like Dr's are, finally, targeting immune system and inflammation as possible root causes. Now, if only there was a drug available that could modulate the immune system and control inflammation (safely) across the blood brain barrier.
https://www.sciencealert.com/alzheimers-might-not-actually-be-a-brain-disease-expert-says