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Gonna be a strange day.. up due to COVID therapeutics play or down due to faith in FDA/MESO/STEM cell conspiracy news??
What if they are the hostile take over?!? A wolf in sheep's clothing? Buy the board seat, sow distrust in leadership, bring on their pharma friends, yada yada
That's what I thought coming into September too. That the board seats were going to be "bought" by Cloverleaf but it didn't happen so yah.. this company is transparent as mud.
Zami and Yaki are NOT 10% owners the form you posted clearly it does NOT have the 10% box checked like clover leafs form. Just compare the two for a quick second. They would need to check the 10% box, they are directors so use the same form as clover leaf, that's all. Your crazy theory is just a theory. Clover leaf must know something though... Why else would any entity buy so many shares in Pluristem
What's everyone arguing on here about? You do realize they aren't actually going to complete their COVID trial anyways.
LOL, when this guy posts sell, it's buy buy buy.
I really thought we would've heard about the board seats by now, I mean does no one even want to work with these guys or what? What the hell is the hold up? I'm sure our next news will be CLI data delayed to Q1 2021 due to reinstated lockdowns.
Mostly a waste of money, but it did raise their market cap which enabled Yaki to reinstate the c suite salaries and bonuses for the board which then enabled their 1 million free shares. Basically todays release was screw off if you are here for Covid news which they conveniently released after granting themselves all free shares and patting each other on the back... It's actually stomach turning. One week saw like 15+% more dilution and more delays.
I stand corrected!!
If the product does not have significant results this stock will end up like STSA overnight. Great risk Great reward. Don't bet your retirement on management that has consistently missed every target they've set and directly misled investors multiple times over. Then literally gift themselves a million shares... If PLX-PAD us not successful this will literally be the biggest joke of a company in history
Yes, I believe you are correct but I'd still argue that's unfortunately unproven as well and no one seems willing to give their therapy a chance. It's been several months, it's quite sad. Hopefully it picks up and I'm wrong
Not sure why my credibility matters I'm still a shareholder but here for CLI. My current stake is about 6000 shares so I care for their success. Just everyone here is scratching their head for answers on why our covid trials aren't taking off after leadership told us in recorded broadcasts multiple multiple times it was a top priority and would happen quickly. I'm providing a possible answer other than deep state, lmao, that's all
Ya, don't get me wrong I'm not saying it's not the cure or that it doesn't work. What I'm saying is I wouldn't blame pluristems clinical trial woes on clinical trial design, deep state conspiracy etc. The fact is clinicians may be hesitant to give critically ill hypercoaguable patients such an absurd number of intramuscular depot injections.. It's very nice as a last resort product and that's probably how it will stay
ya, but none had 30 IM injections... You can bet your lunch money on that. The number of IM injections is absolutely unprecedented for any approved therapeutic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711246/#:~:text=Intramuscular%20injection%20in%20the%20anticoagulated,expressed%20in%20anticoagulation%20treatment%20guidelines.
Intramuscular injection in the anticoagulated patient
Patients on anticoagulants should ideally avoid IM injections because of the risk of hematoma formation; this risk is expressed in anticoagulation treatment guidelines.[21,22] IM injections may cause tissue injury and may also puncture small blood vessels in their way. Nevertheless, many studies have documented the relative safety of IM injections in anticoagulated patients.[23,24,25] It has been suggested that if IM injections are required, sufficient pressure should be applied at the site of injection for a sufficient period of time to ensure that there is no leakage of blood into muscle tissue.[22] Whereas we might have administered depot antipsychotics to our patient in this manner, it is uncertain whether a depot drug would have elicited response when oral medications did not. However, given the past history of repeated noncompliance, it is possible that our patient will default on clozapine, as well, making maintenance treatment with a depot antipsychotic a necessary consideration.
Planned IM injections in patients on oral anticoagulation treatment can be undertaken by discontinuing the anticoagulation medication for a short period, such as 3 days, and then resuming the medication after the IM injection.
Pluristems therapy was never a practical fit in my opinion. Who wants to run a clinical trial where you have to administer 30 IM injections in patients that are hypercoaguable and on therapeutic anticoagulants.. Let alone possibly receive 30 placebo injections. With all the potential options out there this seems like a it's disadvantaged to start. Compare it with a company like ACRS which announced they were starting a trial less than 60 days ago and had first dosed in less than 30 days with only 1 site participating and only needing 40 patients for their phase 2 with placebo, yah the patient severity isn't apple to apples but they will finish their trial with lightning speed. Mostly the reason for this is simple, it's an oral tablet...and not 30 injections.
Just my opinions
ATM active again, wolf selling in chunks to induce fear and drive price down to rebuy via ATM. Anyones guess how low they want it to go. This is all just my opinion.
It says in the S3 that the ATM was signed eith Jeffries already. So that is happening if shelf goes through
Its been a while since i posted here. For a second i actually thought they did the right thing for shareholders with the EIB loan but now its clear after reading the S3 that they have no intention of keeping the loan and will pay it off with shareholder dilution per their norm. The EIB loan was structured before COVID enabeled them to hustle their share price back up to reasonable dilution territory (and their bonuses etc reinstated) so they got lucky. What really erks me is the $75 million ATM in the mixed shelf. WTF, thr ATM is what enabled thr massive manipulation IMO because nobody with $$$ had to play fair, just push thr stock down and grab ypur price point.. That means the stock price could just linger all over again and start the slow drip down before another spike for the phase 3 or not happens. I really hate thr ATM. Also recall in february or march they said they were discussing with FDA etc. the situation regarding data around their trial and they would updste the shareholders, its been like 4 months and we have no clarity on what the hell is happening to the data.
Thanks Jimmy, not something i knew about, will keep an eye on things. Dont get me wrong if this goes anywhere near early april levels I will hop back in some more
I really want this company to succeed but i was sticking around for CLI readout as last hope, Covid gave me an opp to get out with 15k profit instead of 80k loss, just wish i got out last week instead.., they moved that date twice for CLI in the past week!!! How is that defensible.. Rachel said August clearly. Yaki said Q4 today. That was the last straw for me but i intend to follow closely and will be content with being late to the party this time around instead of early.
I exited 90% of my position today because of that statement. I dont care if i miss another swing up due to covid trial news or not. I am not waiting around for them to restate their bonuses and kick the can down the road 6 more months for a topline readout. Its also been WEEKS since we have heard about anymore Covid patients, we comoletely missed the opportunity there. Im just gping to put my money to work other places until september and ill look at things again then
I didnt really understand their delay to quarter 4 for interim CLI data. He said something about not having access to the sites to get the data? Seems really odd, everything should be electronic, what age are we in, lol
click the second event link here
https://www.pluristem.com/events/
Direct link
https://signing-ceremony.eu/
working fine for me
The survival stats werent statistically significant anyways
All i have to say is its pretty bullish to take on 100m debt for a company that has never done so in the past instead of diluting shareholders (again), ignoring what they may have done with the ATM this month, at a point in time that they likely are aware of CLI data to some extent, IMO
Ramakanth concluded, “In light of the medical urgency and Pluristem’s readiness to deliver on this promising treatment, we believe the company could complete the initial studies and report results before the end of 2020, with the potential to launch PLX-PAD for the treatment of COVID-19 as early as 1H21.”
what the heck are they talking about with end of 2020 and 1H21? Thats Pluristems fiscal accountIng year right not literally next year?
They make a unique link for each person that registers, the webcast is saved in the link theY give you after registering. Give that a shot?
i relistened, she said hopefully within the next few weeks. after minute 36
3 weeks, that is what Rachel said yesterday during the QA session when questioned about approval for the multinational clinical trial. im noy sure why people are expecting something to be released today or this week..
I agree with that, but it makes me wonder, why the heck wouldnt they use pluristems off the shelf solution rsther than trying to make their own? Cost??
The article says that they got the Idea from Pluristem but they actually used cells directly from university of Miami, not Pluristem, this is the same university that beat them to the punch with the clInical trial approval... Is it a good thing to have your idea stolen by an american university and then beaten to the punch??
wow, i actually didnt know, i made my first after hours trade today just in time.. maybe..
no reaction AH yet though, i grabbed 1000 at 7.85 tho
so the NJ guy self extubated himself, that enough to get pluristem out of this slump??
https://www.bloomberg.com/news/videos/2020-04-16/holy-name-medical-center-uses-placenta-cells-to-treat-covid-19-video
definitely a pig who just wants to break even
Whats the hold up woth announcing the clinical trial? I know one option is to release when TASE is open but im wondering about other things behind the scenes. Is it a government funding or partnership situation? This indication more or less wasnt truly on the radar 6 months ago why not partner with pharma rather than go it alone again?