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update on website:
April 02, 2013:
NanoLogix has been informed that they have been granted a patent in Japan for the Company's BNP detection technology. This is the first granted patent of seven patents pending for BNP throughout the world
The medical group practice of (a part of ), UT Physicians offers the most advanced technologies [\b]with a personalized touch from its flagship location in the Texas Medical Center and at a growing number of clinics throughout the greater Houston area
Remember the alexa website? I thought it was interesting to see what queries people made to get to Nanologix's website.
http://www.alexa.com/siteinfo/nanologix.com#
Judging from the top queries, I think many professionals are looking for more information about Nanologix products specific to their particular bacteria of interest.
solution: BNP to culture the sample and BNF with aptamers and antibodies to detect and identify including antibiotic sensitivity. If the guys at WHO aren't 'bought' by the money behind the other technologies, WHO will fast track the adoption of Nanologix technology for the good of everyone.
At this point, the company is still vulnerable to mishaps by those with motivations to harm the company. I'm fine with waiting until the company is more financially secure before we bring in others' influence.
Dunno, but I expect sales for antepartum testing to begin this year.
Great! Ok, then my bet if for a BNP COA.
I'd bet money that additional COAs are added this month.
You're no dope. From what I've read, you know more than most about Nanologix. You're not too far off the mark with your three year target for the faster BNF application. It all depends on whether a human study followed by clinical trials are necessary. It took ~1.5 years for this most recent paper by UTHSC to be published from when the study began. So far, I'm not aware that they've begun signing up participants for a new study with this faster assay.
Calm down abig. I am not saying anything about Dr. Faro. Did you even try to understand why Nanologix characterized Dr. Faro's study as BNF and Battelle's study as BNP even though both use BNP?
If you recall, Battelle's paper focused on showing that BNP was no different than growing TB on standard culture other than it provided much faster results.
In the paper you refereced (http://nanologix.com/cms-assets/documents/43512-438183.nnlx-gbs-ajp-research.pdf), the primary focus was to confirm that filtering using antibodies worked. Hence, the experiment is set up by filtering controlled GBS only samples. If the filter works, then growth on culture means GBS is present and no growth means no GBS. They could've used either BNP or standard culture to grow the filtered sample which is why I think this study is characterized as BNF.
From the company's updates webpage:
Jan 22, 2013: NanoLogix Inc is pleased to announce that the results of the University of Texas Health Science Center - Houston (UTHSC - Houston) Clinical Study utilizing NanoLogix's BNF technology to detect and identify Group B Streptococcus in pregnant patients have been accepted for publication in a noted peer-reviewed journal...
Also, from the resources page:
Central Association of Obstetricians and Gynecologists . 2012 Annual Meeting
Poster Presentation - October 17-20, 2012
Group B Strep research from University of Texas Health Science Center
Jonathan Faro presents one hour results utilizing a refined BNF Assay.
http://nanologix.com/cms-assets/documents/caog-10-2012.pdf
This is a poster presentation providing an UPDATE of ongoing testing of GBS with results under 1 hour.
Check your facts. The Battelle paper used BNP to detect TB. UTHSC used BNF to detect GBS. If you read the scientific paper carefully, the researchers said that along the way, they discovered that results could be gotten faster (with BNF) by making changes. I believe they began this faster method as soon as they finished with the original BNF study.
Dr. Faro says based on his study, the BNF method used is good for women before labor. The new quicker version, if proven successful, will also capture women during pregnancy.
I wish I had been listening to NPR science Friday when they were talking about the superbugs aka CREs. I missed a PERFECT opportunity to call in and tell them about Dr. Faro's paper, BioNanoFilter and antibiotic sensitivity test!!
I did forward the article to Bret three days ago and did get the following response:
"Already working on it."
I hope people appreciate how rare it is when such a reputable organization, in our case UTHSC, puts out a PR mentioning Nanologix, a pink sheet company, by name, with a glowing endorsement. 99% of the time, its the pink company trying to get a bump in their share price by suggesting relationships with well known institutions that don't exist.
Abig,
To recap, we are both pro licensing, partnership, etc., but we disagree on how aggressive the company should be going about it. You want the company to actively solicit others because you feel that the company is having difficulty penetrating the market with BNP and will experience similar difficulty with BNF. I think opposite on all accounts.
Your view is premised on your belief that things aren't going well because the company is being mum about sales. That is a myopic view. We won't know the bigger picture until we have a few more Qs behind us.
You mentioned Betamax vs. VHS. Are you aware of a viable threat to BNP and BNF? If so please clue us in.
You also shared your thoughts on BNP and BNF still needing clinical testing and being at least three years out, respectively. You are painting your picture with very broad strokes. The IVD space is huge and varied. Some applications may require a rigorous study like those performed by Battelle and UTHSC, but others may require validation testing that is not so rigorous and time consuming especially since the institutions previously mentioned already did the grunt work irregardless that it was done for specific bateria. There is now some comfort by others to use BNP and BNF and that level of comfort will only grow as more people adopt these technologies. Bret would not be producing BNP kits if customers weren't buying them. I know this because he hasn't produced any BNF kits yet. I think he'll begin producing BNF kits soon...much sooner than in three years.
We know that Nanologix is working directly and indirectly with the government and has been for several years now. We know what the EPA has said about what they think of Nanologix technology. Did you consider this time in your consideration of BNF being three years out?
Nanologix is not pre revenue. They are making sales and I firmly believe they are growing and the coming quarters will show growth to be accelerating. When the players in this market space learn of Nanologix, they will see the writing on the wall. The advantages of BNP and BNF alone would have done it. The packaging is icing on the cake. I realized the implications of BNP and BNF almost immediately; the only concern back then was could a tiny pink sheet company with no revenues survive and endure. Obviously they have.
If someone like me who doesn't even have a background in this space can come to the realization that BNP and BNF will displace the traditional petri plates and put other technologies like PCR and flow cytometry in the realm of niche markets, then players in this market space will too. When they realize Nanologix holds all the cards, they will also know that their choices to stay in business are limited to asking Nanologix for a seat at the table or develop a competitive technology. I am bothered by people suggesting Nanologix would be better off going to others when it should be the other way around.
If they come with an offer good enough for Bret to entertain then I will be comfortable knowing that the value is likely fair. Until then, forget pursuing others for deals other than signing them up as customers. I would feel differently if Nanologix was having difficulty taking market share. Until the financials show me this, I am a firm believer that this is not the case!
Right now, Nanologix holds all the cards. Eventually, as Nanologix grows their share of the market, there will come a time when these guys with money will come to Nanologix begging and outbidding each other for a seat at the table. Until such time, I am satisfied with the path Bret is taking.
The foundation for your argument is an assumption that someone out there, say company A, is willing to pay Nanologix to put themselves (A) out of business sooner than later.
Abig,
Parents's reply to your post already captures one reason why I don't think licensing out flatpack is not a good idea. Besides, would a company like Hardy go thru the pains of modifying their machines to be automate flatpack packaging? In the time it would take to implement such a change and make their money back, the market for the traditional petri plate likely will have shrunk significantly.
This leads into my second reason. If market theory is sound, the graph of the adoption of BNP and BNF will be an S-curve. BNP and BNF is also where the high margins are at. All effort should be put towards getting BNP and BNF out there ASAP in order to shorten the time to reach the top of the S-curve.
I finally got around to watching the Hardy video. I understand your point to be that Nanologix will find it difficult to be able to produce product at a rate necessary to meet anticipated demand. However, what they have now is scaleable. At some rate of production, it will become cheaper to install an automated system such as Hardy's vs. hiring staff, installing more equipment, and expanding the manufacturing facility, but now is certainly NOT the time to make such a capital investment. The machinery is not off the shelf and will certainly require much customization to include being able to install the membrane for BNP between the nutrient agar. It will also need to be capable of producing BNP plates, staining plates, BNF plates (whatever that might involve), etc. Finally, it will need to assemble these plates and package them in flatpacks. Easily a few million dollars and much time for the engineering, product development, manufacturing, installation, training, and maintenance. What volume of petri plates need to be sold for the numbers to make sense?
So, I wholeheartedly disagree with your opinion:
"So the point being if Bret thinks that he can start out by doing it manually and then when we get enough money he is going to build a facility he is making a huge tactical error in my opinion."
If Bret is able to obtain a traditional type loan and is able to finance such a project while making profits, then I say do it ASAP. Fact is, loans are hard to come by for a startup, particularly one that doesn't have a track record (yet) of profits and growing revenues. Easy for armchair CEOs to say things off the cuff, but one shouldn't make judgements of the CEO's performance based on assumptions one THINKS is true.
Wow! First super TB and now CREs!!
http://www.npr.org/blogs/health/2013/03/05/173526084/infections-with-nightmare-bacteria-are-on-the-rise-in-u-s-hospitals
Those who are trying to stop Nanologix's products from becoming the standard for detection of bacteria better hope they or their loved ones don't get one of these superbugs.
At least you aren't calling for Bret to step down in this post. If you are sure he is aware of what you think ought to be done, then why such a long winded post about it? I'm not saying your ideas are bad. I just think that second guessing Bret's abilities are unwarranted considering what he's accomplished so far. With the experiences he's had and the qualifications of the people who we know of that support him, I'd bet that he has access to many others whom he's consulted with as he felt necessary.
In the world of pink sheet and even in OTC stocks, CEOs abuse investors 9 times out of 10 (likely more) by using them as piggy banks for their own personal gain. The typical scheme is to:
1)make agreements with toxic financiers.
2)reward themselves huge and undeserved compensation packages made up of generous stock option.
3)put out fluffy PRs to pump up the share price so that their toxic finance partners and they can sell at inflated prices to naiive investors.
4)when the OS bumps up against the AS, do a reverse split and repeat steps 1-4.
5) show little or no progress in generating revenues let alone developing a product to sell.
Nanologix hasn't exhibited any of these characteristics. And yet, some have the opinion that the CEO has cleverly worded a statement in the latest PR to trick investors to assuming there are sales with money changing hands and not just the company giving away tens of thousands of product to customers to try out.
I've said this before and I'll say it again. As evidenced by the above scenario, the path to riches for the CEO of a pink sheet company is simple, well traveled and without much risk of retribution. Given all that is known about Nanologix and the progress its made to this point, anyone having a shred of doubt that the CEO is engaging in activity to dupe investors is not right in their head or has an agenda to hurt the company.
in 3Q, when $60k in revs were reported, the following COAs were posted on the website:
3Q 2012
8/30/2012 : 1ea. BNP TSA kit
6/5/2012 : 3ea. TSA kit
7/17/12 : 1ea. TSA kit
Since then:
4Q 2012
11/19/12 : 1ea. RBA kit, 1ea. TSA kit
11/19/12: 2ea. BNP TSA kit
1Q 2013
1/21/13: 1ea. BNP TSA kit, 1ea. BNP RBA kit
1/22/13: 1ea. RBA kit
This is an obvious indication that sales are growing. More importantly, demand for the BNP is outpacnig demand for TSA, which is what I expected and what any investor should expect. It looks to me that the super competitive pricing of TSA with EL packaging has opened doors for demand for BNP, and why would customers go back to TSA when there is BNP TSA available?
It IS the product.
Like I said, 4Q results will surprise, but 1Q 2013 will blow us away.
You have a cheap cheap company with an innovative product in a multi billion dollar market. Replacement cost of adopting this new innovative product is the cost of an incubator, which is ~$300? All the benefits of the product PLUS the benefits of the packaging for micro additional cost per unit. The company has been under the radar, but now is out of the gates and with word spreading, so will their ownership/dominantion of the market.
So say there is a Group of investors who are aware of what this company COULD potentially do, but also aware of the high likelihood of failing leaving it open for an even cheaper takeover. What's the strategy here? Wait and see while accummulating shares on the cheap ($0.30-$0.50). But the last 2-3 years, the stock has been so thinly traded that it would take many years of buying to obtain a substantial number of shares in this range quietly -- that is, accummulating as many shares as they wanted without quickly driving up the share price.
They tried taking out stop losses without much success. They tried taking the share price down using paid bashers to create fear and doubt in an effort to scare weak minded longs into selling. They tried creating an illusion of longs dumping to get out, but what is <200k shares a day on a stock with 120m shares outstanding? Do you really believe such pitifully small volume is a sign of longs rushing for the exits?
I'm proposing as a possibility a strategy opposite and far more devious to taking out stop losses. Say, for example, the Group wanted to get as many shares as they could up to $1 (likely much higher). They could implement a multi pronged strategy to get shares.
1. Create fear and doubt by:
a. Capping any run up of share price on good news.
b. Hire paid bashers.
c. Drive share price down below everyone's expectations.
As they do this, they collect shares from stops, those who come to believe something is wrong and those who think that they can get back in cheaper.
They target a bottom that is so low that at their target of $1, the returns (5x at current share price of $0.20) for most retail investors who bought near current prices is so good that most sell out to the Group somewhere on the run up. As for those who have bought higher and suffered thru the losses, they are conditioned into taking profits to avoid suffering thru another drop in share price. The genius of this strategy is that the Group recoups all their shares spent to drive the share price down and then some as they buy up all shares available up to what they value the company at.
I learned the most about running a business from a guy I worked for who was the most morally absent person I knew. He was a very successful businessman. He told me it doesn't matter how much you rip off a customer as long as they are satisfied with their purchase. Applying it to this example, the Group will have ripped off everyone who sells too cheaply, yet all those that sold will be satisfied. The problem is that the basis of their satisfaction will have been manipulated.
The point of this post is not to claim that this is happening. Whether it is or not is moot since the parties involved, the sellers and buyers, will have mutually benefitted.
The point is: Beware those of you who do not truly understand how big and game changing BNP and BNF is even without considering the advanced packaging. Some of you already admitted not grasping how large a competitive advantage the packaging is and that is a very simple technology to understand. Now that management has brought BNP (and eventually BNF) to market, there is no stopping the eventual dominantion of the IVD market space and obsolescence of the current gold standard. The availability of the product itself will ensure this because BNP/BNF is THAT good. Management's involvement going forward will determine how quickly all this happens.
Unless you plan to watch this like a hawk and are lucky at timing your buys and sells, I'm positive this stock will be in the $0.20s soon. Not saying that this will be the bottom. That remains to be seen based on financial condition at that time.
you know what warrants at 0.65 mean to toxic financiers? it means they could short the crap out of ooil without having to worry about being squeezed and it means these toxic finaciers are motivated to see that the share price goes as low as possible. Riggs should never have engaged with such folks, but what do you expect from someone who puts his personal financial well being ahead of investors. How much is he paying himself again?
For those of you who may not have been around long enough to know, management has basically done the following:
Put our fluffy PR after PR to get retail investors to buy at as high a price as possible all the while knowing that they would be selling to accredited investors at steep discounts. In other words, they are their own shills. You see the irony of this? By putting out PRs to keep the share price high, they get the best price possible from accredited investors knowing that they will demand steep discounts to PPS value and volatility. In court, they can claim this was done for the shareholders' benefit even if it meant enticing retail investors to support PPS levels at much higher values.
Management is bereft of integrity.
Mods, please provide permalink to the following address in the company info section: http://www2.mlo-online.com/features/201104/nanologix-ceo-accelerates-the-rapid-detection-revolution.aspx
Some good info for understanding BNP, BNF and their area of market strength.
"The BioNanoPore test kit is a sandwiched-membrane culture technology that provides the ability to see live-cell bacterial growth faster than other methods."
"The BioNanoFilter test kit provides the ability to specifically identify those bacteria detected within minutes of initial detection."
"The future of labs. The industry is improving detection in a variety of ways, and advances in technology and testing are taking laboratories in two directions. Depending on the populations they serve, some advancements might make labs more specialized, while others (like ours) are making live-cell bacterial detection simpler and less expensive."
"Are the recently pulished TB article and hopefully the forthcoming GBS articles enough to start generating sales,...?"
That is what is hoped. I don't think anyone can say for sure, but if management thinks so, then I believe them since they are closest to the customers.
Don't forget, beside the TMC paper, the EPA expects to have some papers ready to publish soon. The next 3-6 months will be exciting.
thanks for the reminder. it'll be interesting to see if there is a spike from it, particularly if it far surpasses its previous ranking record.
i picked up on the law aspect of not using the best available technologies from parents.
BNP may not the be all end all, but comes dman close when used with BNF. PCR will have a niche market where dna analysis is necessary or wanted.
In the recent Battelle paper, PCR was used to confirm the exact strain of TB to validate BNP. This is one application where PCR is relevant; to validate other unproven diagnostic technologies.
Some genetic markers can be associated with specific antibiotic sensitivity. But PCR and other molecular diagnostic technologies cannot determine whether the bacteria is alive or dead. So any application of PCR alone to determine the treatment of detected TB or other bacteria is limited to blasting it with a battery of antibiotics without knowing whether it is alive or dead. Or positive detection needs to be followed up with culture (BNP).
With BNP, you'll be able to identify the bacteria and whether it's alive or dead. With BNF, you can determine which antibiotic is effective in treating it.
Like I said, PCR's real benefit is very limited without even pointing out the costs associated with its use. Also, any analysis by PCR needs to be followed up on with culture (BNP) for effective treatment, whereas BNP and BNF alone allows for effective treatment.
Thank you VERY MUCH for sharing the knowledge you have gained thru your years!
It is odd how things just seem timely. For example, just last week I called up FINRA asking where I could get the trading data for OTC stocks similar to what they provide for stocks on larger exchanges. I was told there is none available and the guy on the phone didn't where or how I might obtain it, even if I wanted to pay for it.
i don't get why you had to bold cap this.
hoping for 3Q financials soon. Given that we have been told that 12k units have been sold (I think this was in August) and a poster on Yahoo said they visited Hubbard and confirmed its been shipped along with follow on orders and assuming continuing sales since the commercial launch of TSA and BNP TSA, 3Q should be the first Q of revenue and should continue to grow once the marketing campaign kicks in.
you'd contact your employees at the SEC? All kinds of wrong with that statement.
1) is it in your job description to be reading/posting on message boards?
2) you work at the SEC and don't even know your own regs?
I'm not certain, but perhaps it has to do with the period of expiration once filed? If you are really curious, you should ask the company.
look at the financials. you can see how previous PIPEs and shares issued for services were priced relative to the pps at the time of the transaction.
if there has been a PIPE, i doubt you'll have anyone broadcasting it. the company isn't allowed to talk about it as it would violate the rule about not soliciting its availability. not sure about the disclosure guidelines for the buyer.
speculation, but I think the PIPE filing was simply to have a facility to raise cash quickly IF necessary. There is enough cash as of the latest financials to cover operations excluding "costs of FDA applications, NanoLogix-funded studies, other tests of our products by third parties, and new patent applications." (from the company update). Anyway, none of the shares acquired thru a PIPE can be sold for at least a year.
Post on YHM by kphone2000 today:
My wife and I made it to Hubbard, the day after labor Day, we spent around 1 hour with Bret.
Bret, was easy to talk to, nothing really new, little tidbits that IMHO, do not warrant a news release. For example, we now have either 15 or 16 machines vs 11. The order of 12k that was mentioned in a PR, has shipped, along with follow on orders. And other orders as well.
We were able take a look at the clean room, from the outside of course. It has the appearance of having been done by a professional, even entry to the viewing area is controlled, dust and likely contamination pretty much eliminated with pads that remove most anything from soles of your shoes. There is a area for changing into the clean room garb. A viewing window is in this area.
Air purification is critical to the lab and production area's, both work on positive air flow and are constantly monitored electronically. State of the art air filtration, helps protect these areas.
There is still plenty of room for production, even with the lab having been carved out of that area. The lab looks good, a bit small, but adequate for now.
Bret, is tight lipped, I think we all know that, I happen to like his keeping details close to the vest. I believe, a low profile at this stage, is smart business. No reason to wake a sleeping giant at this point.
Those individuals looking to make a bundle quickly, are going to be disappointed. They may be able to trade now, but, in the not too distant future NNLX is going to become a premier stock on the OTC. NNLX is an investors dream, IMHO.
I am in it for the long run, even more so, now that I took the time to visit and get a feel for “The man”.
I like Bret as a person, he is a Vietnam Vet like me, it feels good to have met him for the first time. I now know of his dedication, I have confidence in Bret, he is my man. I have no doubt,steady progress is being made. I am 70 and would love a quick buck, but this is going to take time.
I will not sell
per alexa.com, traffic rank as of 9-9-12 6:33 et is 52,472.