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From your lips to God’s ears.
Who fired her? Who is making these decisions? Maybe it’s a suicidal firing?
That sounds very high tech. Do you think it’s therapeutic to deliver a drug whose efficacy hasn’t been established in a phase 3 study and FDA approved?
What is your reasoning for saying, “ they have the connections to advance Brilacidin”? How do you know that? Is there a connection between Laser development, software engineering and infectious disease and anti-microbials? This sounds more like “hope-e change-e” thinking and trying to keep your audience for company?
Post# 355737 4/15/21 9:43 AM, Post 355775 4/15/21 12:28 PM, both, as you can see, by The Poster Boy for Credibility. Your further comment ?
BTW at he posts I checked weren’t yours, PJ owns them.
I did the koolaid thing too and I wised up way too late. I still hold a fair amount of shares but it has been a big mistake overall. I believed what smarter people (most) than myself said and I kept buying. There isn’t going to be any $10 or $15 Billion valuation, generational wealth, Lamborghini or great unions at a fancy restaurant where all the would be newly rich shareholders stated their intentions to “buy” with the money they were going to make. My feet are on the ground and the page has been turned.
Angus, if your credibility rates 3 question marks ???, then how many ? marks are warranted for referring to Leo (post 335737) as “CEO of the Century”. Or , “I believe Leo’s bottom number is $10 Billion, take all. I believe he can get it”. (Post335775). There are dozens and dozens of such posts by PJ littering the IHUB IPIX landscape. Yet, he features himself the “POSTER BOY OF CREDIBILITY”. Wear your scorn with honor, you’re in good company with the Ranger.
“We know that early stage biotech investing is a very small investing group due to the large failure rate in the sector.
We know that those that do elect to invest in this sector have finite personal funds available for such investment and from what I have heard over the years those of us already in are pretty much all in by this time. Thus, further investment by this sector is decreasing all the time.
Now that I have listed those that won't invest in IPIX at the current time, who will invest? I wish I could list a whole slew of sectors but I can't name any.
Thus, we are at the mercy of those that play trading games with low volume start ups. There is no genius involved in being able to manipulate the share price, in fact it is quite easy at this point in time.
Thus, longs suffer in silence and wait for the worm to turn and it will only turn thru the continued successes of our trials and the infusion of large amounts of capital from partners. Those same partners won't become available, per our CEO (Leo), until after P2s are completed and we haven't reached that time yet but it is on the very near horizon w/ Prurisol top line results due out any day now. That is when we hear how Leo will take the company in the future and shortly thereafter we should hear something about a deal being signed. Just as you can't have a winner until a horse race is actually run, you can't label IPIX a winner or a loser prior to when deals could be announced and that cannot happen (per Leo) prior to the P top line results getting PRd.
Until that time, we must rely on mgt and to date they have done us proud bringing all 3 drugs to advanced stages of clinical trials with no failures on IMO minimal finances and dilution of stock. Our drugs will be targeting revenue streams in the many, many tens of Billions of dollars per year. BPs currently are running on nearly bare pipelines and have tons of cash for investment. Besides handling the clinical trials and financial sectors admirably as evidenced by official results and filings, they keep stockholders informed via PRs. I find it incongruous that they would handle the first sectors so efficiently and then handle the PRs in a careless and deceptive manner as is voiced daily by those harking for the demise of the company. If Leo says he has 20+ CDAs, I believe him. I believe in the science of the drugs so I also feel he is dealing in negotiations from a position of strength. When it is time for him to show his cards, I expect to see a winning hand.
Am I positive about all the above, no, but all evidence to date leads me to believe in mgt and that they are dealing in a manner as straightforward and competent as possible.
IMO mgt has earned the right for support from their stockholders and I will believe in them until proven facts show otherwise. I will not be swayed by ludicrous opinions and obvious lies from a contingent with an obvious bias against them.” Canoli, is this the accurate and useful investing opinion that you believe is benefiting your investing or did you merely get carried away in appreciation of the views within?
Mack, I truely hope that IPIX succeeds and sells for $5 per share and all our board member’s fantasies come to pass, even George who valued the company at $15 Billion. I have been here before your arrival and I still hold many shares. It is clear you have a hard on for the Ranger and that you spend far more time than is healthy or wise trying, unsuccessfully, to torch him. If anyone on this board has posted useful information on IPIX that informs logical, sound decision making it is the Ranger. He has been steady and consistent with his research and explaining, what to most of us, is tedious and complicated. Had I followed Rangers clear indications I would have saved myself many hundreds of thousands of dollars, a great deal of time and, yes, grief. I believed Prurisol was set to dethrone Otezla, and 70% of those tumors, resident in unfortunates, would be history with our Ca drug, and, of course “B”, which simply did EVERYTHING. I listened to pumpers and I did some myself. People smarter than myself, which are most people Farrell, old Grump in NJ etc and, I followed interesting pumpers who wrote in colors, italics, and boldface print and Ranger remained consistent and stable. There has been tons of money lost on this board by following and buying into the pumpers and those who live in fantasy and counsel it. A better way had been before me and I listened to the noise.
He, Blues, like the Ranger are just fine. Take for yourself what you can use and leave the rest. Remember that some think your opinion isn’t so hot either.
And , I image, he has to remain sharp to do Aerobatics in his plane named “RANGER”. And he would be required to have mental dexterity with all neurons firing for competitive kickboxing against the competition and you.
I did. Sudoku and finding golf balls.
I’m sticking with Sodoku and Golf balls. And it seems to me that there are at least two types of people in Ipix. Guys who like being coaches and quarterbacks and those who fit the role of cheerleaders. Separately are your Dunns and Maxdudes.
And he takes the Kickboxing and he has a nice rig for the Aerobatics which is costly
Neither you nor Mr Ehrlich have credibility in my book and I believe the Ranger before you, no offense. So, do I now get to give you an assignment as you gave me? Please find the Rangers post giving his portfolio ( about 5-6 stocks as I recall) and merely calculate their value then and now. That task is simple for a wise man like yourself but way exceeding my capabilities. When you have done that, you know what I am going to say, match it up to IPIX. Express your comparison in percentages. Then weep.
Are you nuts? You want me to do forensics on 100+ boards for what end? I have time for that nonsense? Or the capability? Ask thr Ranger, he can handle whatever problem you throw at him. I am a mere mortal. I am afraid though that if you ask the Ranger he will respond with my first sentence. Maybe you would be wise to buy the Rangers portfolio, so you can at last claim to hold good stocks. He gave it to you at one time about 5,000 posts ago. You can even calculate how green you would be now.
Those are not facts. Some retired guys do Soduku and some scour the periphery of golf courses hunting for mishit golf balls. I imagine the Ranger keeps his mind exercised studying Ipix. He uses many aquired skills that have the capability of helping others. I wish I had listened and acted accordingly. Has a guy been better off following you or the Ranger. As is said, your best thinking got you to where you are now.. you decide.
Jeez PJ, with that response you did yourself no favors. With your own reasoning you explained why the Ranger has no losses and you sit atop a pile of dung, exhorting victory is at hand. Where you going with that reasoning?
You might find it more informative to study the parallels between IPIX and “ A Weekend At Bernie’s”.
The Old Testament.
I wonder if Brilacidin (small molecule) can be considered for development to enhance the coverage and effectiveness of vaccines? Maybe somebody can pose the question to Dr DeGrado other than me, I have questioned him enough.. J&J, PFE, AstraZeneca can all use a “boost”. “Brilacidin the Adjuvant”.
Excellent post.
There will be plenty of oral treatments in the mild market and an ittraveinous player will not be able to compete.
I would hope the direction of where we go from here with Brilacidin is more determined by DeGrado than Leo. Maybe B doesn’t work on viruses in vivo and the monies we have will only allow one more try in an area where B has failed. We know Ms Wolfe cleared Covid after 10 days treatment but she might have been past redemption at that point but if the tx was begun at an earlier stage……? DeGrado could give input on other indications for treatments maybe with Asthma or Copd (PDE4 and anti-inflammatory) via nebulizer. Could be done as POC P1/2 in hospital or by pulmonologist in out patient setting. Doseing determined inP1 and nebulized with an in line set with O2. That could be a low cost trial yielding lots of data and validating B via nebulizer and opening the door to Covid at early stage and competitive with the announced orals by Merk/Ridgemont and Pfizer. We can’t just roll over now. Leo is good at scrambling and surviving and this is a big challenge.
Wasn’t the estimated cost of P3 for ABSSSi estimated at 30 M in 2013 as I recall? We do have a shortfall for a P3.
And, Dud, .40 is the BRICK WALL?
https://www.cbsnews.com/news/alzheimers-costs-americans-277-billion-a-year-report/
Being able to reduce this expenditure is compelling. Doing a screen of people who have or had a history of Herpes prior to B treatment and how B effected Herpes might be interesting.
https://www.precisionvaccinations.com/herpes-simplex-virus-and-neurodegenerative-diseases-linkage-identified
Considering that Alzheimer’s is on course to bankrupt Medicare in the not too distant future and if you use the above article as argument, it would be wise ro have an effective tx for Herpes. If this becomes true, B as tx for Herpes, then a strong petition can be made for funding to advance B for Herpes to intervene in development of neuro degenerative disease. Just a thought. Thinking RBL work on B for Herpes could already be started.
You have made my points. Thank you.
Having done thousands of them I an aware of every aspect. If you read back on my recent posts about prophylaxis you will see that I got the responses I sought. A teaching moment.
B is not in a hospital formulary.
Nosebuzzers
And I bet you would think private insurance would not cover the 5 day infusion? And maybe the government wouldn’t pay either because a 20 dollar vaccine would cover prophylaxis?
So, taking that reasoning a bit further, all of those unvaccinated who are waiting to receive B as the savior will also have to become infected with Covid 19 before they are candidates to be saved by B? Wanna take a ballpark to how much longer they might have to wait with a target on their backs before they can get an infusion? So B will be used same as the MABs?
If B were to be given prophalactically any idea when that could be available for non infected people assuming good TLD? Would additional trials be required with IV administration as a prophylactic? We would be using B the same a a vaccine,no?
Thanks for your good post reinforcing the need for treatments. I found this for background info on vaccines and the immune compromised which is present with all vaccines and the immune compromised.https://www.cuimc.columbia.edu/news/are-immunocompromised-patients-left-out-covid-vaccines
Brilacidin—-soon.
The first acct that I was using still looks pretty bad but I averaged down in the other ones and I am “not bad” now. The first account I became self conscious with the broker about my losses so going forward I used the other acts. It’s embarrassing to admit. Ok TMI
I am here about 8 years and I have bought through the length of the journey and I haven’t sold one share either. I always read your posts and I appreciate your knowledge of clinical medicine and how that informs your posts. I am optimistic about TLD and I believe we will do better than a pair of Jacks. Good luck with your investment and life.
Nice to read an informed logical post. Thanks.