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60% Acquisition Premiums In 2010 For Biotech Sector According To Leading Industry Analyst
Buzz up! 0 Print..Companies:Acorda Therapeutics, Inc.Halozyme Therapeutics, Inc.Seattle Genetics Inc..Related Quotes
Symbol Price Change
ACOR 35.74 -0.28
HALO 8.42 +0.30
SGEN 11.70 +0.16
VPHM 13.65 -0.12
{"s" : "acor,halo,sgen,vphm","k" : "c10,l10,p20,t10","o" : "","j" : ""} On Wednesday April 7, 2010, 12:44 pm EDT
67 WALL STREET, New York - April 7, 2010 - The Wall Street Transcript has just published its Biotechnology & Pharmaceuticals Report offering a timely review of the sector to serious investors and industry executives. This Special feature contains expert industry commentary through in-depth interviews with public company CEOs, Equity Analysts and Money Managers. The full issue is available by calling (212) 952-7433 or via The Wall Street Transcript Online.
Topics covered: Clinical, Financial & Regulatory Risks To Drug Development - Easing Capital Markets - Managing Inherent Volatility - FDA Approval Process - Small- & Mid-Cap M&A Rally - Basket Investment Approach - Impact Of Health Care Reform - Therapeutic Cardiovascular Plays - Investable Trend In Antibody Technology
Companies include: Genentech/Roche (RHHBY); Medivation (MDVN); Seattle Genetics (SGEN); AEterna Zentaris (AEZS); Abbott (ABT); Alexion (ALXN); Amgen (AMGN); Antares Pharmaceuticals (AIS); Ardea (RDEA); Astellas (4503); AstraZeneca (AZN); Auxilium (AUXL); Biogen (BIIB); CardioGenics (CHNG); Celera (CRA); Celgene (CELG); Celldex (CLDX); Corcept (CORT); and many more.
In the following brief excerpt from the Biotech And Pharmaceuticals Report, expert analysts discuss the outlook for the sector and for investors.
Dr. Jason Kantor, Ph.D., joined RBC Capital Markets in 2005 as a Managing Director and Senior Biotechnology Equity Research Analyst. Previously he was a Managing Director and Senior Biotechnology Analyst at WR Hambrecht + Co. from 2002 to 2005, and Vice President in Equity Research at JPMorgan Chase & Co. from 1998 to 2002. In 2004 Fortune magazine ranked Dr. Kantor as an "All-Star Analyst," and The Wall Street Journal ranked him second in its "Best on the Street" survey. Dr. Kantor received his B.A. cum laude in biology from the University of California, San Diego, and his Ph.D. in cell and developmental biology from Harvard University.
TWST: You mentioned the small- and mid-cap M And A rally. Would you talk about that for a minute?
Dr. Kantor: What I mean by that is in 2009 we saw Medarex and Genentech (DNA) taken out; we've already seen OSI Pharmaceuticals (OSIP) in play in the past weeks, and we've seen Facet (FACT), which was originally a target for Biogen (BIIB), ultimately getting taken out by Abbott (ABT) at a significant premium to where the Biogen deal was proposed. What we are seeing is a number of small- to mid-cap companies and, in some cases, large companies that are the targets of acquisition. Whenever that's the case and whenever you see companies paying 40%, 50%, 60% or more premium, you begin to see the other companies with similar profiles reflecting increased valuation.
TWST: Who are your top picks right now and why?
Dr. Kantor: Our 2010 pick on the large-cap side is Celgene and on the small- to mid-cap side is Seattle Genetics, another pure-play antibody company with a deep pipeline of proprietary and partnered antibodies. And then I would add to that list, if you have a slightly longer time horizon, Cubist (CBST), which has proprietary antibiotics, which they sell directly with over $500 million in annual sales and growing. And we view this as the value play based on its low price-to-sales ratio.
TWST: When you are weighing companies, what do you look at? What are the most important factors for you?
Dr. Kantor: They need to have drugs. Whether they are early stage or late stage, they need to have good drugs that meet unmet medical needs, that have good patent life, that have high margins and that have very good growth prospects. Every successful biotech company has been built around a drug - in some cases one drug, in other cases more than one drug - but I think that's the one defining component in biotech, is you got to bet on the winning drugs.
TWST: What about trends in this sector? Will 2010 differ substantially from 2009 for the sector?
Dr. Kantor: Obviously there are no clear delineations along calendar years. Everything is a continuum. What I would say is that we've been focused for many years in the area of antibodies and antibody technology. I think it's been a fruitful area for M&A and for deals. I still think it's going to continue to be a great area for the development of new drugs. So I won't say that's a new trend, but I think it's a consistent trend and more importantly an investable trend.
TWST: Are there advantages to biotechs that develop therapies for orphan diseases?
Dr. Kantor: There are certain advantages of developing drugs against orphan diseases. One, you get additional exclusivity for your drug, which means that you can fend off potential generic competitions for longer. You also, in many cases, can demand much higher prices. And for very serious orphan diseases that are life threatening, there may be a lower hurdle from a safety perspective and a clinical data perspective relative to larger markets, such as diabetes or hypertension, where there is plenty of competition and a very, very high safety hurdle.
TWST: Is this a sector investors should be invested in?
Dr. Kantor: It's very attractive to the individual investor because there are so many stories of fabulous returns, but I would definitely be cautious in that respect because there are very few sectors that have the kind of volatility that we see here. For every winner, there is usually more than one loser. I think it's exciting, it's vibrant, everybody can relate, people have family members and friends with diseases, and can relate to these treatments and potentially cures in some cases. But it is definitely a sector that is fraught with danger.
The Wall Street Transcript is a unique service for investors and industry researchers - providing fresh commentary and insight through verbatim interviews with CEOs and research analysts. This Special Issue is available by calling (212) 952-7433 or via The Wall Street Transcript Online .
The Wall Street Transcript does not endorse the views of any interviewees nor does it make stock recommendations.
For Information on subscribing to The Wall Street Transcript, please call 800/246-7673
Sure is IMO!
If it's vague and cryptic.....
Same old, same old, and EVERYBODY HERE KNOWS IT (but just may have not come to terms with it)
I want the best! I am long like most and have just about had it!
A while back I even considered getting some other PPHM investors together to take a legal whack at these guys but the fees were to damn high to get it going. Wish I could of sold some PPHM to pay for it! LOL
Either way, I think this is the end of the Crazy train!
All Aboard.....Or maybe down with the ship!
We find out on the 14th!
Guys (and Shoop did-aly Loop), This earnings coming is it!
Let's face it, if it is the same old, we're screwed!
If they have news, salami!
It is a 50/50! The only difference, and I mean only, is that we had some "MOTHER OF ALL OF THEM" trading days, which begs the question: WHAT THE HELL WAS THAT ALL ABOUT?????
Guess what boys and girls, IMO I think we are about to find out!
EARNINGS!
This will be the biggest event/nonevent of our little flaming birds history!
IMO, we have come to the boiling point! RS Looming, Cash Burning, data promising, Cotara Settlement, etc.
This is it!
We're either gonna eat steak or s?(*
No in between, cause, let's face it, at this point, there no in between. We either have money from some type of deal, gov't,etc. or not and that means they WILL do the big nasty, as history has proven time and time again!
I feel this time it is different but you never know the chick is packing sausage until the dress comes up!
Well boys and girls, get ready for the show!
Please be beaver!
Regards,
G-Daddy
Realist, thank you for the reply! belive it or not, I do appreciate the cut of your jib, I just don't buy it all the time! (PS-Same is true for the Mas Pumpers!)
So, if PPHM is not up to their old tricks, what do you think now????
$6M+ avg. trade vol.
<500k short?
Based on you logic, they are NOT up to their old tricks! So do you feel that we may have turned the corner?
Realist, are you confusing the short interest with the average daily share volume????
WHY DOES NASDAQ SAY ONLY A 40.85% change???? Oh that's right, you know more than NASDAQ!
Short interest for:
06/15/2009 496,451 40.85 6,463,807 1.00
http://www.nasdaqtrader.com/Trader.aspx?id=ShortInterest
Your so freakin desperate!
Realist, was the DTRA a poor deal?
As a matter fact, b/c is was a negotiated deal, I would think that the HAVE proven themselves in 1) bringing in a deal EVEN AFTER IT ALMOST DIED DUE TO BUDGET CUTS, and 2) They can bring in money (EVEN IN A BROKE ECONOMY), a la the $10 Mil financing DURING THE WORST FINANCIAL MELTDOWN SINCE THE GD!
Looks like they can handle themselves, hope you can after this week!
Good luck, it was a pleasure having you around but your predictions and time have run out faster than PPHMs! BWA HAA HAA!
BTW- If you need a job bashing other stocks after PPHM closes over a $1.00 for 10 days and gets $$$$$ for dealing COTARA (which HAS happened), post your resume (I'm sure ubuy2, CHEVY, or CW can hook you up!), or, can we just use your posts from the last 2 years as reference items? You were by far THE BEST BASHER we have come to read on these boards! Intelligent, master manipulator, and persistent!
G-Daddy
Oh no! Does anybody think that some orders may go away from Avid after this ac.??? Hope not!
Xcellerex Announces Sale of FlexFactory Bioproduction Line to Crucell for Vaccine, Monoclonal Antibody Manufacturing Facility
http://finance.yahoo.com/news/Xcellerex-Announces-Sale-of-bw-1956500450.html?x=0&.v=2
I really don't think we have seen anything yet!
I have a feeling that the limp Cotara PR we get on Tuesday will be followed by volume higher than 36mil.
If someone is coming in to play, that will be the last day for them to really load up!
Oops...we still have the Duke Paper!
Interesting times,
G-Daddy
WH-
I remember the days of Aruba on RB!
Katie
Rich
Frootie
MissPPhm
John Alaska
Terry
Etc.
I think we were all just early!
Screw Aruba,
TO THE MOON!
G-Daddy
KT-Thank you. I guess where I got confused was at the bottom of the link is shows that there can be additions or deletions up to the 19th. So technically, we're still not out of it? Sorry, not pumping, just dreaming. Am I off base here or do I read it correctly?
I guess we didn't miss the Russell after all????
Looks like we have till the 26th of June?
http://www.russell.com/Indexes/membership/Reconstitution/default.asp
KT-
I hear you.
Thanks,
I was just trying to get these two to make a move!
Slippery, the same goes for you! If you look at all my past posts you will see i show you nothing but love! Problem is, they may have the goods but they also have 4 months to come up with some cash and get over a buck to avoid a RS. This is of course is they respect the current share holders and actually want WS to show them some respect. So what do you say to the same bet??? If there is no reverse split and they get funding by October then you can give the adios to anybody you want! If not, then nice knowing you!
You have been dead on with quite a few things (almost as much as realist) so either your in the zone or playing in it!
It will be interesting to see if either you or realist take this bet!
My Prediction: Neither one of you step up!
Realist this is the 1st time I think you have made some sense. How about just a simple bet, if they pull a reverse split and PIPE you can choose to kick anybody off this board, if they don't you leave!
Pretty easy bet! What do you say?
BTW, I really enjoyed this last post. You bring up some great points and truth be told, are probably closer than a lot of others. Whether we hate on you or not, you are more correct than anybody else on this board. The problem is that your telling Fat people they are FAT! We know this investment is a dog, we know that this ASCO was a thumper followed by a limp ass recap! Problem is, why are you posting if you own no shares? That's where your credibility falls apart. And without you disclosing why your actually here, even if you were telling the truth and dead on about the last 10 days, nobody is going to listen to you!
Sorry bud. So what do you say on the bet? It's a very clean bet and if you feel convicted of your hypothesis, than it is a no brainer.
OK got it!
I do not agree with it as I think it is a hell of a lot more than just a PR on Cotara, but that is the bueaty of the US....FREE SPEECH!
I then apologies to you and redirect my other response to the douche bag who thought that Thorpe is unhappy....what a dink.
Rattle are you serious? You think Dr. Thorpe is upset that the United States Gov't is interested in Bavi and that it is being manufactured in Tustin???
Please.....
OH MY GOD IT's GROUNDHOGS DAY!
This is what Adam F. from the street.com had to say about PPHM LAST YEAR at ASCO!
Doesn't sound too much different w/ the exception of the 7.4 PFS
http://www.thestreet.com/story/10420029/1/feuersteins-biotech-stock-mailbag.html
Hey, PFS is exactly what is sounds like, right?
For example,
On average, tumors started coming back around 7.4 months?
Is that good?
Thanks,
G-Daddy
Biotech Stocks and the ASCO-Effect=PPHM Mention
Here's some late night PPHM love:
http://seekingalpha.com/article/140552-biotech-stocks-and-the-asco-effect?source=yahoo
Thank for the WHOLE article. Wish yahoo would do the same!
http://finance.yahoo.com/news/Immune-system-taught-to-fight-apf-15391323.html?sec=topStories&pos=4&asset=&ccode=
Dear Lord, please tell me this is Bavi!!!!
-Taken from Yahoo!!!!
Immune system taught to fight deadly skin cancer
First-of-a-kind treatment trains immune system to fight deadly skin cancer, doctors report
* Marilynn Marchione, AP Medical Writer
* On Saturday May 30, 2009, 3:33 pm EDT
*
Buzz up!
* Print
ORLANDO, Florida (AP) -- For the first time, a novel treatment that trains the immune system to fight cancer has shown a modest benefit in late-stage testing against the deadly skin cancer melanoma.
The approach is called a cancer vaccine, even though it treats disease rather than prevents it as most vaccines do.
Doctors say that in a study of 180 patients already getting standard treatments, the vaccine doubled the number of patients whose tumors shrank, and extended the time until their cancer worsened by about six weeks.
Results were reported Saturday at a cancer conference in Orlando.
I think were gonna get 3 PR's on Monday.
1) Bavi in GA
2) Mono Bavi
3) Nature Article
If we get all 3,
See you guys at $2+
G-Daddy
Goat, if you click on Date, there are no real seelers at all this year!
Only sun trust with about 19K!
The last big seller was Zimmer at the endo '08
Good Riddance!
You mean kinda like the Dios PR?
DEAR GOD I HOPE NOT! Not only was it a bogus PR, bit we missed it by 1 penny!
Last post,
Click on date to sort date, etc.
Sorry for the sloppy links.
Your right realist, thank you goat for pointing it out. Isn't the last group of names on that list (especially Zimmer) associated with R&R and the pipe factory???
http://www.nasdaq.com/asp/holdings.asp?symbol=PPHM&selected=PPHM&FormType=Institutional
Oh yeah, and nobody has sold out in '09 Those numbers are from last year!
http://www.nasdaq.com/asp/holdings.asp?symbol=PPHM&selected=PPHM&FormType=Institutional
Actually, the only institutional action this year was WELLS FARGO ADDING!!!
http://www.nasdaq.com/asp/holdings.asp?symbol=PPHM&selected=PPHM&FormType=Institutional
Suck it realwad,
Looks like real $ could be on the way.
There are 9 sites in India Testing Bavi with Breast Cancer.
hmmm.....must not be working.......
Realist, take a stab at that one.
CJ, Better add a 6th site to the Bavi Mono trials.
Locations
United States, Arizona
Arizona Cancer Center Recruiting
Tucson, Arizona, United States, 85724
Contact: Jeanette Cardenas 520-694-9082
Principal Investigator: Linda Garland, MD
United States, California
Premiere Oncology Recruiting
Santa Monica, California, United States, 90404
Contact: Marilyn Mulay 310-633-8400
Principal Investigator: Lee Rosen, MD
United States, Tennessee
The West Clinic Recruiting
Memphis, Tennessee, United States, 38120
Contact: Tracy B Stewart, RN, BSN, OCN 901-683-0055 ext 1236
Principal Investigator: Lee S Schwartzberg, MD, FACP
United States, Texas
University of Texas Southwestern Medical Center Recruiting
Dallas, Texas, United States, 75390
Contact: Mary Padilla, LVN 214-648-7039 mary.padilla@utsouthwestern.edu
Principal Investigator: David E Gerber, MD
Scott & White Hospital, Center for Cancer Prevention and Care Recruiting
Temple, Texas, United States, 76508
Contact: Kericha Kennedy 254-724-5890
Principal Investigator: Lucas Wong, MD
MD Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Contact: Jeanine B. Williams, RN 713-563-4527
Principal Investigator: Nuhad Ibrahim, MD, FACP
OK, tell me this isn't BAVI?
OK, so I am flipping through the UCLA extension Summer Class catalouge and there is an ad on page 128, in the upper left corner, a course titled Fundamentals of Immunology with a picture of what I think is Bavi kicking some butt!!!! Can someone else confirm that this is what I am looking at?
Thanks,
G-Daddy
As far as Rodman goes they came along with the deal!
"So, we'll set up the PIPE for you and it comes with 1 yr. of "coverage"!"
Rodman was never truly interested in us. They just hooked up the pipe and then fell off when they were told that PPHM would no longer "renew"!
Question is now, OK if Rodman is no longer at the table, where is the money coming from???????
Makes ya think....but not hard!
G-Daddy
PPHM and MEDI were both cross!!!
Your a dingus!
They we're going at each other! They both has something to gain and lose.
DON'T YOU GET IT????? LONGS GET TO SHINE!
Geezzzz.....dingus!
Clearwater,
BOTH parties dropped it!
329 REQUEST FOR DISMISSAL (WITH) FILED BY MEDIBIOTECH CO INC; SHANGHAI MEDIPHARM BIOTECH CO LTD ON 04/22/2009 04/22/2009 MEDIBIOTECH CO INC; SHANGHAI MEDIPHARM BIOTECH CO LTD ON 04/22/2009
Sorry, chump, nice try! Better luck next time!
Anyone think we get HCV-HIV info on Monday from AACR?
GDaddy
I think Georgia data comes out on Monday!
There is no better place for Thorpe to come out at!
It will be a battle royal of scientists on Monday in Whistler and this would be the perfect place for Thorpe to finally get some big Kudos comming off of the Nature Article!
Come On Phil, Take it to task on those dorks from DNA. Show them our geeks have bigger brains then theirs!
CJ-
WE ARE NOT IN DISCUSSIONS WITH ANYBODY IN REGARDS TO SELLING SHARES. (or something like that by PL in '07 and then, SHAZAM!)
Weren't we all struck by that on too?
Sorry, had to throw it out there?
I can't believe that we ended red today!
WTF!!!
Actually, everything is in place. If these dingbats execute the RS I am pulling the trigger (along with a few family members). I could care less at this point what it does to the share price. As far as I am concerned, these guys are on their last leg. It either happens or it doesn't. But a RS at this point is unacceptable. Way too much potential not to get a deal done and avoid delisting. So, to answer your question in earnst, we are ready! Family attorney on hold, let's see what the weasle's do!
1: Why the Cotara pull back?
Enrollment is taking too long! Money better spent on Bavi!
2: Why no PR's for Bavi Georgia in 5 months?
New round of tests for the second phase of that trial.
3: Why no Duke paper after it's been talked about for more than a year?
3 months and counting till it hits. I'll won't post even again if it's not the case. Will you stop if it does?
4: How many shares of dilution if they try and raise that $7.5 million needed to get the 2nd loan traunch?
That's "IF" they need it!
5: What are the most likely effects of a reverse split?
House of pain.
Pretty easy.
Now how about you
Why do you really post here?
Thanks CJ, just checking on the Mark S. thing.
G-Daddy
What the heck is going on with this trial???
Active, not recruiting Safety and Efficacy Study of Bavituximab Plus Paclitaxel and Carboplatin to Treat Breast Cancer
Condition: Metastatic Breast Cancer
Intervention: Drug: Bavituximab
http://www.clinicaltrials.gov/ct2/results?term=bavituximab
Does this mean we have already enrolled everyone into it already?