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Every corporation that has one leader and 100 percent yes people around him / her is considered to be an unhealthy situation ..
The part that irritates me the most is Chris just lies to the investors
And if we need a p3 , at our glacial pace , will be at least 5 years 6 months so obviously opportunity costs makes this investment prohibitively expensive . Just for once Chris get yo act together
And that I believe is the biggest strategic weakness of the missling and the board .. a bunch of directives half finished sitting in purgatory.. let’s just say your boss gives you 4 directives to COMPLETE .. instead of starting one and finishing it and going onto the next one you decide to start everyone and different levels of completeness and then seemingly take a year off and seemingly have no ambition or urgency to finish each task .. the boss is gonna send you to the unemployment line and that’s where the whole Avxl team needs to be .. a complete change up is warranted
I’ll use an analogy .. 20 horses in a race and I’ve placed my money on the horse in last place and trailing badly .. but miracles do happen !
I’m still amazed how many folks openly support and explain away every delay and misstep .. like I don’t believe it’s appropriate to bad mouth one’s own investment but this is an anonymous board where truthfulness and credibility scores a 1 a out of 10 and of course people’s true agenda is always murky but still our current price and MC is as plain as the nose on ones face . No ambiguity here .. it sucks so bad !!
So SAVA distributing warrants valued at 33 with an expiry of a year. Seems like an out of the box financing scheme drivng price to 33 .. is this interesting or noteworthy.. the fact that missling is the finance guy raising money at grossly subdued value here .. I wish he would go … I have no reason wishing he would stay
There is virtually no market enthusiasm in us . Bot 2000MS at 73 few weeks ago .. only thing keeping the arsenic on the shelf :(
Anybody but missling and I might share your enthusiasm
I’m gonna medicate so this day can just go away. :( .no shiny bicycle and probably barely enough for a feed of lobster .. :(
Sp500 tops level seen almost 2 years ago . Just does not seem to be any interest by management here to hit timelines reminiscent of other biotechs. Some believed apparent delays was covid related but ain’t no covid restrictions now for months and months and months .. while our share price languishes near uplisted price some 8 years ago :(.
We came to the market with a reverse split onto the Nasdaq. … without Wall Street money. This fact has plagued the stock price from that moment
It’s been a disappointing year , just another disappointing year .
No worries Sab .. I do enjoy reading your posts and we’re all big boys here but this stock sure can be depressing and I suspect even more so for those with afflictions in the dementia space
Ya it’s quite possible the price might go up and it’s quite possible the price could go down . You did think the .7.50 area would hold weeks back only for it to crash under 5 so no offence your no more credible than that ‘god bless ‘character .. but still even a blind squirrel can find a nut so let’s hope 9.50 by Christmas and 50 by Easter !
Ya disappointing that after 10 years not even a rumour of a partnership or buyout and , and , Avxl is so unliked by the market that even huge deals with lesser compounds can’t even spark our share price and some of us here know where the weakness is
I hope so !
Ya dumb people loose money but I’m not dumb but I must be dumb because I lost money here . Well I haven’t looked for a while but my 3000 shares have been sliced and diced and I’m left with 1 or two shares at 16 cents while that scammer lives the big life .. well good for him . The ride to the top of the market through 21 was euphoric but the fall has been tuff . Stick with top 100 S&P companies
Lol
This stock is terrible and it’s performance relative to others is even worse
He knows the expectation based on his projected timelines. Fully expect ‘ something’ regarding Rett TLD and probably last week of December
But really fellows for last 10 years the most significant and unknown data point that is released in these Q reports is the level of cash and debt . To expect more is puzzling
And
Rett syndrome: On track for top-line data of potentially pivotal ANAVEX®2-73-RS-003 Phase 2/3 EXCELLENCE pediatric clinical trial.
It takes a team effort to stay in these trials and results must be real or you get a drop out .
Probably not cause Avxl has no cred . If a partnership was announced with a bigger g player then perhaps. As far as insomnia and the new patent announcement that runs out in 2037 so no revenue there with regards to insomnia
Ya a partnership.. some say no real news for several months or more or NOTHING beyond Rett but a partnership announcement could come any day and would push us 10 dollars higher in an instant :)
Ok ok but today go baby go want to run down to the pound and buy a dozen lobsters and celebrate ,,, celebrate .. cell—- a — berate market down up to15? Pennies
PW
You have been a staunch supporter of Chris and the anavex team , I hope you are richly blessed . We were given a gift in 21 ( we should have accepted it and ran for the hills but dummies like me held on for more .. I have cut my holdings in Avxl but still hold enough to save my pride and perhaps a 911 but we need revenue which means approval somewhere .. may the force be with the CEO and the BOD and retail investors
I keep smelling what seems like the barbecue but the burgers and steaks still seem like a mirage
Did you see this coming ? 2 takeaways… the company really does believe in their data and two .. the lack of serious AE’s and ease of administering is BIG !! Lol
NEW YORK, Nov. 20, 2023 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental disorders announced today that representatives of Anavex met with team members of the European Medicines Agency (EMA).??
These meetings discussed the debilitating pathology of Alzheimer’s disease and Anavex’s blarcamesine (ANAVEX®2-73) Alzheimer’s disease clinical program results, including data obtained in the ANAVEX®2-73-AD-004 study.
Pursuant to discussion at the meetings, Anavex initiated the process for submitting a Marketing Authorisation application to the EMA with the submission of the Centralised Procedure request with the goal of the Authorisation allowing direct access to the market of the European Union for oral blarcamesine for the treatment of Alzheimer’s disease.
Anavex’s goal is to take care of patients in a patient-centric way with the preference for convenient oral treatment options for Alzheimer’s disease not requiring complex logistics resources and added personnel for drug administration and monitoring for brain edema and brain bleeds.
Severe symptoms in relation to Amyloid-Related Imaging Abnormalities (ARIA) is a known risk factor for Alzheimer’s patients taking the class of drugs called monoclonal antibodies, and requires constant and repeated MRI examination, for which not all regions in Europe are currently sufficiently prepared and equipped for in addition to the requirement to address affordability and inequalities in patient access within European Union countries.1,2
“We look forward to working together with the team from EMA,” said David Goldberger, RPh, MLS, Senior Vice President Regulatory Affairs at Anavex. “We continue to work towards fulfilling our purpose of improving patients' lives with oral blarcamesine not requiring any complex additional procedures for the treatment of people with Alzheimer’s disease.”
There are an estimated 7 million people in Europe with Alzheimer’s disease, a number expected to double by 2030, according to the European Brain Council.3
The World Health Organization (WHO) estimated the cost in Europe of caring for people with dementia, including Alzheimer's disease, at $439 billion, or $31,144 per person in 2019. That includes hospital care, medicines, diagnostics, informal caregiver time, community services and long-term care facility costs.4,5
“There remains an urgent need for convenient once-daily oral treatment options for Alzheimer’s disease, and Anavex is moving forward to potentially addressing the preference for simple patient-centered administrations and shared decision-making,” said Christopher U Missling, PhD, President and Chief Executive Officer at Anavex.
In addition to significant improvement in dementia symptoms, blarcamesine demonstrated reduction of pathological aggregation of amyloid in early Alzheimer’s disease as well reduction of brain volume loss, a well-known marker of neurodegeneration.
Data from the blarcamesine in Alzheimer’s disease Phase 2b/3 randomized clinical trial will be published in an upcoming peer-reviewed journa
Because the fact is we do have a large short position against the shares :)
Perhaps today is the day with additional releases of material info is the start of our quick and big short squeeze or maybe a longer slower uptrend but still hoping for ‘ other ‘ announcements
Been hearing this message for years
Ya really would love to be a fly on the wall . Is there any urgency to get this data out ? What are the reasons for the tardiness? Are they even in the office today ?
I never expected Chris to mislead to the extent he has . .. to speak and create expectations based on what he actually says and articulates in press releases and those expectations are never fulfilled on specifically two different timelines A ) the timelines that have been generally accepted based on hundreds of prior trials completed last patient dosed and release of TLD and B) his own stated timelines that seemingly are never met and additionally, seem to be grossly late compared to traditional timelines
Now we know why it’s so easy to boil a frog alive .. we are just as smart or just as stupid as a frog
About to explode and what ? Cease to exist ! I’ve come to realize that investing and trading around interest rate risks .”, the fed , and all other current events is demonstrably easier than investing and trading around the disturbing and utter opaqueness of Avxl and Chris .. I’ve reduced my exposure to just 1.5 percent of my overall portfolio and just an observation of mine ; those who pump always have money to buy lower and lower
Still disappointing that AVXL trades so poorly and particularly now with SAVA trading at a market cap twice of that of AVXL with its warts and inconsistencies
I don’t believe a word you say ..
I’ve been reading posts like this for 8 years now ( that’s a lot of days ) we’ve been beaten up , beaten down , beaten all around .. even if we bounce 100 percent now won’t cover inflation costs , gas costs , opportunity costs , funeral costs !!
I sold a bunch at 10.41 back in Feb. really did not wish that I could double my shares 8 months later but right now if I double my shares don’t know if that is really smart or really stupid . I did learn my multiplication tables as a 6 year old and learned 5 x0 is zero and 10x0 is zero so twice the shares x zero is still zero so maybe I’ll wait a while until the crystal ball is a lot more definitive
Nothing to talk about , nothing to discuss , nothing to muse about , nothing to be proud about , nothing to feel good about , nothing to validate about , nothing to vindicate , nothing . Maybe that’s why he’s been quiet