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Bertolino was hired to shepherd the lucrative low hanging fruit (P) through a successful P2 and position it for monetization. He failed and was fired. P could be tweaked and tried again but not until the company is in a comfortable financial position. It showed great promise. B was tweaked and look at where we are now. At least Leo didn't risk the company's future on P like Polymedix did on B. Leo is not a scientist and does not bear the brunt of P's failure. Bertolino does. Leo gets credit for letting him go, not jeopardizing IPIX future like Polymedix did and moving on to what's next. K's development/financial needs were slowed to a crawl and Krisha put on the bench. Good job. Leo is managing this well. B kept making progress and is now in a game changing position due to the "pandemic." If all of the info we've received thus far is legit, we are about to garner the right kind of attention and blow the lid off the suppressed share price. Leo's played the long game which kept us alive, and by chance, put us in the pandemic position we're in. Hasn't reverse split us. Hasn't taken on debt to bankrupt the company. It's been painstakingly slow but I think a new day is about to dawn.
Perhaps it seems the RBL and PHRI are taking their time because they got a new "toy" and haven't finished "playing" with it yet. These kinds of institutions are not known for speed. Correct me if I'm wrong but it seems we get new information about testing B in ways and against cells unexpectedly. These are not profit motivated institutions. They are funded and can take as much time as funding/budget allows. This has been a results boon for B/IPIX and results that are incontrovertible. If COVID wanes, Corona viruses remain (common cold, etc.) and all of the other things B has shown potential to treat by the RBL/PHRI testing. I want the price to rocket and I'm frustrated that it hasn't at least pumped and dumped into the dollars and back like the the lesser competition. But B is proving to be the real deal form many, many indications and with it we have a ticket to a changed financial narrative for life for all invested.
Shhh,don't mention HCQ. BECAUSE HCQ was politicized we were presented opportunities to advance Brilicidin. HCQ is "dangerous and deadly" even though the military has been taking it for 50 years for malaria, it's prescribed for lupus, the President was on it for a week and a half, and it is effective against COVID-19 as a preventative and therapeutic especially early, before Cytokine Storm and Co-Morbidity involvement which takes things out of HCQ's therapeutic wheelhouse.
Yes, cause of death: hit by a bus. The death certificate states, "cancer related." Do we shut the country down, mandate enforceable health safety protocols, vilify those who disagree with the liberty infringement and who question the projections and models, call into question the inconsistencies and dishonesties and unconstitutionality and destroy the lives of millions over something that never became what the fear mongers proclaimed?
Even better for my argument. Thanks.
How many who test positive are hospitalized? How many who test positive die? How many who die actually die from COVID? How many in LTCFs who died would have died anyway without COVID or would have died if they caught the cold or flu? I know of 2 people who died this past month who were classified as "COVID related deaths" when in fact they were not. The Governor where I live, who has this place still locked down and talks on camera in her own office, social-distanced, with a mask on, (?!) got COVID, got sick, and recovered just fine. She is elderly. Got it from her son on a Fri. got sick over the weekend and recovered the next week. Nothing asemptamaic or incubation period of 14 days about it. Why are people on TV, who have tested negative, social distancing with masks? It's ridiculous. Protect the vulnerable, and let the rest of us "risk our own lives." Enough with the hyped-up, hyper-partisaned nonsense. If people without masks are a risk to other people's lives then why are the same people who shout it found without masks? Tom Hanks, Pelosi, Feinstein, etc.
PolyMedix, because of debt, had to file for bankruptcy. That's how Cellceutix picked up the B franchise for $5mil. IPIX is not in a bad debt position and has been able to last this long because of it. Sure, the outstanding share count and share price are disappointing but I suspect there has been a huge price suppression conspiracy (far beyond MFO share selling) and a purposeful lack of deal making by potential suitors, and think both are connected to either bankrupt IPIX or weaken it to sell on the cheap. It has to be that because it doesn't make sense otherwise especially with the outstanding B news regarding the coronavirus. If IPIX can just keep plodding forward we will eventually break through. We are just one media covered announcement away. hp
Could the B-IBD pill be used as a preventative for COVID-19?
If in fact B punctures the virus' envelope and effectively prevents (prophylactic) and treats (therapeutic), we are invested in paradigm shifting drug. When I told a nurse who was to draw my blood about B's ability to puncture the virus' envelope, she stopped the screening process and had me write down the ticker symbol. She said God sent me. Apparently she knew the importantance.
Why did you buy penny-unwise?
What was it that made you pull the trigger?
Did you buy then decide to look into things?
You make no sense.
Someone as concerned as you would have checked these things out before hand.
Would have sold over these concerns.
Did you buy Friday on a whim and didn't look into things until after the market closed and now you're stuck.
Sell at the open Monday. IPIX usually opens up and then fades if there's no news.
Stop filling up this board with your pseudo concern.
I'd have to look up his no reverse split statements which is something I'm not going to do for you.
I've read them over the years like many on this board have.
Either believe multiple long time longs who testify Leo's stated it or look them up yourself by reading Leo's different interviews over the years.
Eggs in 1 basket is how Buffet (Geico) and Phil Town (a penny stock bio) first made their money.
You must be new.
Leo has stated more than once no reverse split.
Amazingly, you found the Evan's blog.
Put forth the same effort and find the Leo no reverse split statements.
George Evans was the reason I hesitated to put $ into CTIX.
When he was gotten rid of, CTIX went to the top of my investment list and has stayed there.
The only stock I'm currently in.
All in!
Brilicidin and Kevetrin!
Better if you sell and move on rather than do your little dance on this board.
HP
Leo is a rare OTCBB/Pinksheets CEO, especially in pharma. He did not dilute us and then reverse split us like most do over and over. He did not take on debt that would eventually bankrupt the company. He weathered the take down and constant downward pressure to navigate B through trials to prove safety and efficacy in multiple indications. He kept to the plan of proving the worth of the drug to position it for the right moment(s). There have been disappointments (P) but a moment came for B, COVID, and B was ready for prime time. The moment was seized and look where we are now: on the brink of greatness. Amazing! If this plays out like it should, B will be a wonder drug and Leo a CEO wunderkind. The Regeneron model will be in full effect and those who scoffed at Leo's vision will be the fools in the end. I'm glad I found this gem a decade ago. True, I've sold when it wouldn't hold and bought in again to try it again and repeated that process since I first got in all the way down to .05. Maybe lost a few hundred dollars total doing it that way. But bought a freighter full between .05 and .08, average at .07 and I am up ten thousands of dollars. I am so pumped about our prospects. It's a dream come true. hp
Yes, I think so as well. Momentum could start Monday and quite possibly take it to $1 in anticipation of Grant news. To me, Friday's close was a positive indication that profit taking and consolidation ran its course and the next leg up is getting ready. I could be wrong and the share price could do something different but at this stage, with the kidney and lung results, and Grant submission, it seems like it's game on and sustained, dramatic price appreciation has finally arrived.
Amazing turn of events!
Out of ALL of the stocks $.50 and under (my research niche for investments), IPIX has been my #1 for a decade. I am averaged in @ $.07 thanks to the shares in the $.05's. I have more shares than I ever thought possible. To me, IPIX's B/K platform/pipeline potential is worth more than $100 a share. I don't understand why a pharma hasn't stepped up with $ to help unleash B & K's potential to their shared benefit. I am glad it didn't happen until I loaded up all that I could. This COVID positioning by Leo is a game changer and B has risen to the top like most here knew it would. I hope the Regeneron model is still the guide but now $1 starts to change my financial narrative. It would be/will be great to see the share price bust through $1 and pass it by fast and far. Grant approval news would do the job. Hopefully this coming week. Everyone I talk to on the investing topic I mention opening a Firsttrade account and start accumulating IPIX commission free. As of now, IPIX is my only stock investment. I have 10 others on my watchlist waiting their turn but they will have to wait until this story plays out. I'm all in on IPIX. I have also invested in 3 digital assets but won't mention them so as to not have this post removed. That's it, concentrated like how Warren Buffett first made his money in GEICO that set him up to become the Buffet we know to day. Not financial advice.
Not long ago, I posted that it seemed to me as if Leo was setting the company up for a sale. Though I'd rather become the next Regeneron, I can't help but to think a sale is the course Leo's charted. Maybe this COVID opportunity will change things but I won't be convinced until he starts filling out company positions again. Of course $ determines employee hires and maybe grant money will help. It's been a long haul since 2009 but finally there seems to be real traction for the best drug ever created. And there's Kevetrin still to come. Hoping for Regeneron but thinking it'll probably be sold.
IPIX's B ruins the virus vaccine narrative. If B kills the virus there's no need for an iffy vaccine. A healthier world population (a vaccinated population) will help reduce the world's population by 10-15% - Bill Gates' constant message in his health speeches. Population reduction - just like his Planned Parenthood involved father. Just listen to the speech (TEDtalks?) on an upcoming virus threat that looks an awful like a coronavirus. He and Fauci predicted this current event. All factual statements. Speculation: Predicted or were they aware? Both were in some way connected to the Wuhan lab. Will B be given a level playing field to compete against decades long agendas? So far, so good.
Exactly! Leo has shepherded CTIX/IPIX through the valley of the showdown of death (Micro Cap Biopharma) and seized the COVID-19 moment to put us in a once in a lifetime position. CEO of the decade!
IPIX is in the COVID sweepstakes position it's in because Leo put us there. No reverse split, advancing pipeline on a shoestring budget, trying to affect positive outcomes from positions of weakness, and shifting focus to near term potentials speaks volumes of Leo's Microcap company leadership; not to mention releasing Bertolino over the Purisol disappointment. All that prestige for naught. We all know the rise to $4.90 was a pump and dump and the company wasn't in position to take advantage of the price to up list. The downward pressure of the stock price to bottom out at $.05 gave many of us CTIX/IPIX longs (2009) a once in a lifetime chance to accumulate a ton of shares. "Time and chance happeneth to them all." This is our time and chance moment. If Brilicidin keeps up its Tour-de-force we will finally break through to where many of us believe IPIX is destined. HP
Feels like the company is preparing to be sold. Dr. B's departure was a let down but led me to think perhaps it was to lean the expenses until the company could be sold. It doesn't seem like more development is in IPIX's future beyond what is currently in the works (validation of drug delivery with the pill for B and maybe K). Have to admit, the prurisol fail, Alfa Sigma deal, and Dr. B departure let helium out of my enthusiasm balloon. Now I'll take $1 a share for a buyout. I was expecting a stock for the ages and accumulated shares accordingly but now my hope beyond $1 has faltered. $1 will set me up for future things. Anything less would be a huge bummer. If the company isn't sold, and we do hit $1, I'm selling most to take care of current concerns but will keep 1/4 to see what happens. Maybe a stock for the ages but I've started to doubt. HP
As for me, I'm buying as much as I can as often as I can. IPIX will either max out the authorized shares and reverse split or finally find some traction and begin to become the stock for the ages many of us are expecting. I do have to say the first licensing deal was a bummer. Purisol failure was a huge bummer. Not getting BTD was a let down and the first deal not materializing was a set back. But, what company doesn't experience problems? I understand the anger of the $4.95ers watching the pps sink to current levels. I for one am glad I can buy up shares at these prices. I'm betting IPIX will set me up for the rest of my life. Or I'll loose a few thousand dollars. I don't see a better bet under $5 and I've combed through them all. I'm hoping things turn around in a big way by May of 2020. Hopefully sooner. HP
Back down to pre-reverse split prices.
Took longer than I thought it would.
I told you so.
I'm about ready to buy back in.
I'm going to start building a position a little at a time.
Should find support around these price levels (3.50-4.50).
But, just in case the price tanks thanks to a Chan money raise and a corresponding short attack I'm going to ease my way in.
Still think the tech is transformational and disruptive, but also think Chan did retail dirty with the reverse split proceedings and don't trust him.
Hp
I predict IF a 5+mil. or better upfront payment is PR'd, we will never see these .12-.14 low prices again.
Doesn't seem too farfetched of a prediction to me.
"IBD is ripe for innovation."
What a great line.
It feels like the mood is changing.
If IPIX releases a PR revealing an upfront payment of 5+mil. we are headed higher without never to see these lows again.
A manipulated OTC/Pink stock usually pumps when an announcement like this is made and then dumps 2 to 3 days later.
Based on what happened, it seems to me those guys are not in control of IPIX.
Leading up to the announcement, the price drifted from .19 to .12, spiked @ .24 upon announcement, and then retraced to .14/.15.
Volume was not massive.
The deal was small, no cash up front announced, so I think things played out as one could reasonably expect.
There is a foundation laid now.
Things should start to solidify and IPIX should start to gain traction.
Considering B was scooped up for 5mil. I'd say were off to a good start with 24mil/6% and an undisclosed initial payment for two 2 of the least lucrative indications.
The deal's small and the undisclosed upfront payment negatively affected price action.
If the upfront payment is small it'll continue to negatively affect price action.
Anything under 5-10mil. upfront will be a bummer.
I'll just look at it as an opportunity to keep accumulating shares.
It looks like we are finally on our way but not with the bang I was hoping for.
I think that is correct.
That is one of the reasons that kept me from making an initial investment.
Once George was gone, I was in.
Leo has constantly affirmed no reverse split.
We have come a long way since pre-clinical testing of K.
I for one am glad I get another chance to load up on shares.
I know there are $4.95 "bag holders" on the board howling at the moon and I understand their frustration.
Still, I am glad for the low priced shares, again.
Soon things will change for the better.
I've been investing here since shortly after George Eaves left the company (2009?).
CTIX/IPIX has come a long way since then.
Kept track of the company nearly everyday since.
The only real disappointment was P not meeting its end point.
Then again, I got involved because of K.
The B franchise added multi-layers of cake and frosting.
Leo's done a great job keeping things going in a forward direction without irresponsibly diluting the shareholder and then reverse-splitting.
Those two are my main concerns.
If either of those happen, then my tune will change.
The dilution thus far has been responsible by OTC biotech standards.
If a deal happens soon, then we are off to the races.
A drug with multibillion dollar potential indications for .11?
A rare if not once in a lifetime opportunity.
Worth risking a few thousand dollars for the chance to turn it into hundreds of thousands if not millions.
Dr. Bertolino - "We're not just looking for "more" value; the way we're setting it up, we're looking to "maximize" value. "
I found CTIX when it was .29 and pre-clinical with K.
When it shot to almost $5 I thought I missed a once and a lifetime opportunity because it rapidly exceeded my ability to accumulate shares.
But low and behold here it is at .17 with B, P, and K P2 successful, term sheet signed, and blockbuster(s) potential.
I can (and did!) load my little boat with more shares than I thought possible and wait for my life to permanently change for the better.
$3.75 changes my life, and everything over that will have me happy laughing the rest of my life.
Amazing!
Hp
K was the reason I ivested in CTIX back in 2009.
A SAFE non-genotoxic p53 drug.
No dose limiting adverse effects through 10 p1 dose escalation cohorts.
Putting it in a pill form for ease of use and frequent dosing only adds to its value and potential.
Is it effective?
My guess is yes.
But it is SAFE and that is a huge starting point.
After P and B are on their way, and money is no longer an issue, K will have the spotlight.
There are so many cancer indications for K and cancer maintenance therapy possibilities that K could end up being the biggest $ maker of the 3.
It's speculation, but isn't that what it's all about.
If K was already proven, then IPIX would be out of investment reach for me.
That's why I scour the OTC for investments.
SAFE, non-genotoxic, no dose limiting adverse events or dose limitations, p53 drug in pill form.
Boom!
Enough said!
hp
Are the September milestones a make or break "sitchiation?"
As I understand it, Leo set up the milestone funding agreement because the share price fell below .50 causing the previous 30M funding agreement to be inaccessible.
Am I wrong about that?
Apparently, Leo needed money immediately (CRO, Drug manufacture, sachet prep, etc.) so the not-so-favorable funding was set up.
The new funding arrangement was a bit of a bummer but I do trust Leo's leadership so I'm rolling with it.
One would think that if a license with upfront $ was on the September horizon then why the unfavorable funding?
Don't know, but I bet Leo does.
He needed the money "now" for reasons and a runway of cash for reasons and Aspire most likely required the milestone set up for their purposes.
Will I be upset if milestones are not met and the share price takes a hit?
Not if Leo continues to refuse to reverse split the stock.
I will be buying more and more and more!
You see, I think K, B and P are blockbusters each and blockbusters in a multitude of indications.
And I think one day something huge, massive, and mind-blowing will happen to the stock price either as a buy out or to send it on an upward trajectory that will be the envy of Wall Street.
As long as Leo does not reverse split the stock, I'm good.
hp
BTD Application
BTD - 60 day FDA response time.
Either a yea or nay from FDA.
If yea, company must expedite the development of the drug or BTD could be rescinded.
If nay, the company can reapply.
I'd like to know when Leo submitted the application.
hp
Push The Pause Button on the Negativity
Leo explained the current agenda with milestones to meet and a deadline to beat.
It's absurd to run the man into the ground before the agenda plays out.
I don't expect an update of any kind until an item on the agenda is checked off.
All the predictions of default and demise are premature and futile.
My guess is that the select few who constantly bang on Leo bought the run-up to $4 something and are bemoaning "bag holders."
I can understand the frustration because I pounded the CEO of a certain blood filter company severely for dumping all of the company's authorized shares before reverse splitting for 25/1 instead of 10/1 like he led on.
But, Leo hasn't reverse split nor has he done the shareholder dirty.
Leo hasn't botched a clinical trial yet either.
Leo has shepherded tiny IPIX to a historic inflection point fast approaching.
So, I say to the disgruntled, ease up a bit and let's see if Leo can get your head above water in the near future.
The milestones before us can turn us in the right direction.
Let's see if Leo can execute the agenda he laid out by the deadline.
Post about the possibilities until he actually fails.
The "failed" up-list rants and death spiraling share price chicken little routine is OLD!
hp
Concerning B and specifically ABSSSI.
B/anti-biotic needs a big pharma to take through P3, NDA, approval and to market.
Big pharm has the leverage/marketing/influence to get B/anti-biotic generating meaningful revenue.
IPIX is at a huge disadvantage if it were to go it alone.
Even if B equals dapto in efficacy and its 1 dose versus 7 days is a big benefit, getting it prescribed is a different ball game.
Big pharm has so much influence as to what is actually prescribed through incentives and pressure.
B/ABSSSI is maybe a $500 mil market and to break through to garner market penetration and generate meaningful revenue could be disastrous for a tiny bio like IPIX.
Putting it on pause until a deal is right is the right thing to do.
Glad we didn't start a P3.
Plenty of tiny biopharma companies like IPIX try to take their drug through P3 to NDA on their own only to find disaster.
Money runs out, CRL sets things back, unforeseen trial delays or glitches derail timelines and protocols, CRO's don't hold up to their end of it.
It's extremely difficult for a tiny biopharma to cross the finish line of a P3 successfully and to a FDA approval.
Dilution, reverse splits, etc.
Saying the share price would have stayed $2-$3 for IPIX during P3 in order to raise funds for the company and trial, and fund other trials is pure speculation with plenty of examples to the contrary.
The take down was so severe, a P3 trial would not have warded off the negative effects.
I think the "value building strategy" was/is the right way to go, and advancing Purisol to this point for a deal was the best way to go.
What tiny biopharma company doesn't have things to complain about.
IPIX has 3 potential blockbuster platforms - multiple billion dollar indications from each platform.
I am not expecting news from P's p2b to be the game changer because trial news hasn't changed the share price as expected.
Perhaps P's p2b will change the sp in an upward direction/momentum to up-listing where legit analysts will cover and institutions will invest.
But the game-changing/life altering events happen with big fish partners and licenses.
I expect a deal/license will affect the share price in a permanent upward direction.
If IPIX delivers on its vision, this will be a stock for the ages.
Nothing but progress has taken place.
Share price declines are the norm for development stage biotechs on the OTCBB until there is a catalyst that changes everything like a drug approval or partnership with BIG PHARMA.
Savvy traders/investors keep a core of shares for the long haul and also a trading amount to play catalysts (like the previous pop to 1.15) until the game changer happens.
You sound like what's happening to IPIX is not a normal occurrence for a micro-cap bio on the OTCBB.
My take is that the trolls on this board are underwater with their investment and are barking at the moon because of it.
Even if you bought in at $4.90, IPIX is only a partnership away from leaving that in the dust.
I'm just glad Leo didn't sell us down the river.
The share price performance thus far is par for the OTCBB biotech course.
The up list would not have happened so no need to cry "the missed window, the missed window."
The real window is about to open.
Thank you Leo for not diluting the shareholder into oblivion.
Thank you for not reverse splitting to up list only to have the stock decimated by short and distorters, to be driven down to delisting notices like so many other biotechs who ran too far ahead of natural progression.
Thank you for managing the finances of the company to keep it in the game.
Thank you for developing the pipeline with out handicapping the company with debt (like Polymedix).
Thank you for putting the company in a position of strength to seek partnerships by proving K, P, and B are safe and work.
Leo, you will be the CEO of the decade.