Don't worry bout the mule, just load the wagon.
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You must have overlooked Actinium Pharma. Would be a great company to collaborate with in regards to their pipeline.
Case in point ATNM is pre revenue with slumping financials yet slated to go up from $20 to $50 pretty soon as Ph3 trial almost at a close.
Doubled my money in it yesterday.
As usual, the Lepper Con is all about BS and lies.
HIV Gene Therapy Clinical Trials Based on In Vivo Delivery
Studies employing the in vivo approach in HIV are mainly at the pre-clinical stage. In vivo approaches involve the introduction of the gene therapy product directly to the patient using either viral vectors like adenoviral vectors, adeno-associated virus vectors or non-integrating lentiviral vectors, or through non-viral methods like nanoparticles. In vivo methods may not provide a long-lasting cure, because there is no stable integration of the transgene with the host’s genetic material, and the delivery to specific cells needs to be optimised to reduce the chances of off-target effects. Gene editing through recombinase or nuclease systems [61], or silencing mechanisms using RNA interference or possibly CRISPR-interference, could use the in vivo approach.
Current clinical trials include a study that used leronlimab, an anti-CCR5 humanized IgG4 antibody that competitively inhibits HIV env attachment to CCR5 by binding to the same attachment site as CCR5 (the extracellular loop-2 and N-terminus domains). This agent was administered subcutaneously, and the group is currently working on using a synthetic AAV vector for delivery. Several versions of this study—NCT00642707, NCT02175680, NCT02355184, NCT02483078, NCT02990858, NCT03902522, NCT02859961 and NCT05271370— demonstrated the safety and efficacy of the product, with patients experiencing mostly mild side effects and efficacy being observed at higher doses of 525 mg and 700 mg [221].
Advances in HIV Gene Therapy
by Rose Kitawi 1, Scott Ledger 1, Anthony D. Kelleher 1,2,3 and Chantelle L. Ahlenstiel 1,3,* [ORCID]
1
Kirby Institute, University of New South Wales, Kensington, NSW 2052, Australia
2
St. Vincent’s Hospital, Darlinghurst, NSW 2010, Australia
3
UNSW RNA Institute, University of New South Wales, Kensington, NSW 2052, Australia
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2024, 25(5), 2771; https://doi.org/10.3390/ijms25052771
Submission received: 2 November 2023 / Revised: 20 February 2024 / Accepted: 20 February 2024 / Published: 28 February 2024
(This article belongs to the Special Issue Advances in Gene and Cell Therapy 2.0)
Abstract
Early gene therapy studies held great promise for the cure of heritable diseases, but the occurrence of various genotoxic events led to a pause in clinical trials and a more guarded approach to progress. Recent advances in genetic engineering technologies have reignited interest, leading to the approval of the first gene therapy product targeting genetic mutations in 2017. Gene therapy (GT) can be delivered either in vivo or ex vivo. An ex vivo approach to gene therapy is advantageous, as it allows for the characterization of the gene-modified cells and the selection of desired properties before patient administration. Autologous cells can also be used during this process which eliminates the possibility of immune rejection. This review highlights the various stages of ex vivo gene therapy, current research developments that have increased the efficiency and safety of this process, and a comprehensive summary of Human Immunodeficiency Virus (HIV) gene therapy studies, the majority of which have employed the ex vivo approach.
Loser, knew your written word was worthless.
Go look up restitution, go read the red print and
the cases cited.
$CYDY$ 2024
Lost the grip on those reading glasses appears again R.I.P ?
Admit it, pigeons don't like to drink leronlimab no matter how safe or
effective, nor ivermectin, nor HCQ. Interesting perplexity. Are they even
human? NO! They are pigeons and a leper con. So they battle for a few
pennies over whether or not leronlimab is safe and effective.
Short bashers are great at selective reading. Even then, the problem is
acknowledging they got a problem. Kind of like those who are hollering
conspiracy when all thousands of doctors and scientists who say BS to
the CDC and FDA. Even as the numbers don't lie with dead celebrities
in the news daily keeling over from one secondary Covid problem or the
other 750 side effects recorded. But oh no, let's get in line for the Kraken!!
Belly on up to the jab bar boys and girls.
OH Me O My, looky hea, what just came down. https://www.idropnews.com/news/apple-to-pay-490m-to-settle-class-action-lawsuit-over-comments-by-ceo-tim-cook/210514/
A little bit of restitution.
$CYDY$ Looking for some restitution!
LOL fool. The liberal judge ruled they can't sue as a class action.
The proposed class included more than 200 people who invested in funds between July 29, 2013, and Oct. 5, 2016, for the purpose of buying shares in Theranos, once a star of Silicon Valley.
Cousins said individual lawsuits were appropriate because some investors might be unable to show they relied on the blood-testing company's alleged misrepresentations.
Reed Kathrein, a lawyer for the plaintiffs, said he may appeal or seek reconsideration. (class action)
But wait, there's more. "Theranos also faces a criminal probe into whether it misled investors, The Wall Street Journal said in April."
It ain't over yet baby. So I guess you will be happy when Pourhassan and his CRO buddy cop a get out of jail free Plea. But guess what, this is the SEC/Fed
and not individual or class action which may follow. Either way, the best is yet to come when CytoDyn meets up with AmarX in August... a few months away.
I continue to be amazed at your ignorance. What was posted about Tucker Carlson as your statement made no sense? What favorite network? What has this got to do with the price of tea in China?
OH the restitution for insider trading...will probably be cited by Sidley against Nada et al and then separately of course in Aug against AmarWreck. https://news.bloomberglaw.com/white-collar-and-criminal-law/restitution-for-corporate-victims-of-insider-trading-the-skowron-case
"On March 20, 2012, Judge Denise L. Cote of the United States District Court for the Southern District of New York ordered Joseph F. “Chip” Skowron III (“Skowron”) to pay $10 million in restitution to Morgan Stanley as a corporate victim of Skowron’s insider trading and obstruction of justice schemes. Judge Cote’s decision in United States v. Skowron, No. 11 Cr. 699 (DLC), 2012 BL 652827 (S.D.N.Y. Mar. 20, 2012) provides a useful roadmap for evaluating potential avenues for restitution to corporations that fall victim to insider trading schemes by their employees."
Oh now and what about this baby doll. Damn these people are bad. https://www.justice.gov/usao-mdla/pr/former-insider-convicted-defrauding-baton-rouge-company
"U.S. Attorney Brandon J. Fremin announced today that KATHERINE T. CANCIENNE, age 40, has plead guilty to wire fraud in connection with her scheme to embezzle hundreds of thousands of dollars from her employer, Engineers & Constructors International, Inc. (“ECI”), a consulting firm that provides engineering and managerial staffing to oil and gas companies. The defendant faces a significant prison term, fines, and restitution orders as a result of her conviction.
Wait... you may want to catch up here...and see how the teeth of the law are getting sharper. https://www.akingump.com/a/web/19294/financial-consequences-of-insider-trading.pdf Interesting how the case where all the salary income derived from the insider to be considered ill gotten gain while the fraud was going on. Cough it up big boy.
So now we can know that you cannot read so well because the original post indicated what could occur as to future action resulting from the case and Nada's sorrowful plea deal. Go Sidley.
I missed Tucker down at the Stock Yards this past weekend. He is smoking hot on X and now suing his old boss Fox. Going to be fun to watch. With the whistle blowers coming out of the woodwork from all corners, it looks like there may be some gain subject to forfeiture where the lie was actually the truth as truth surfaces. This then would be compounded. Watch it unfold and the liars and bashers go down.
Yes, thinking leronlimab is what the doctor ordered. $CYDY$ 2024
So will NSF go after AmarX for their failure to disclose the CytoDyn fiasco?
What? Another lying female!! Getting all too common. Move over men, we got fraud to fine tune.
https://abcnews.go.com/US/startup-ceo-accused-175m-fraud-denying-made-success/story?id=98415514
https://www.fiercebiotech.com/cro/nsf-international-buys-up-cro-amarex
I'M bigly bullish on $CYDY$ 2024
1.Elizabeth Holmes, the former CEO and founder of failed blood testing startup Theranos, was found guilty on four charges of defrauding investors, capping off the stunning downfall of a former tech icon.
The charges Holmes was found guilty of include one count of conspiracy to defraud investors, as well as three wire fraud counts tied to specific investors. Holmes faces up to 20 years in prison as well as a fine of $250,000 plus restitution for each count.
2 - 11. https://www.nbcnews.com/business/markets/10-ceos-who-went-boardroom-cell-block-flna783944
Bye bye, go back to the club house cafe.
$CYDY$ 2024
Right O bwolfy2002. I've owned and profited off NVAX a few times. Still have a few and may soon be buying more as a short squeeze is in the works I believe.
Another example being Actinium Pharmaceuticals. My GTC order was filled today in one account booking a super nice gain. Sell xxx Shares of ATNM Limit at $8.41 (Good 'til Canceled)
Filled at $8.41
Case in point ATNM is pre revenue with slumping financials yet slated to go up from $20 to $50 pretty soon as Ph3 trial almost at a close.
As usual, the Lepper Con is all about BS and lies.
Wrong interpretation Grip. "Pourhassan made, and caused CytoDyn to make...."
This is the allegation to which a plea will most likely be forthcoming. CytoDyn was harmed
and may well be compensated as a result of the plea. Let's not forget to add to that the conspiracy that AmarX's
CEO Kazammohamed and PourHouse forged together harming both companies. Betcha Sidley is taking notes.
CytoDyn may wind up owning AmarX. NSI and CytoDyn will be in discussions. Don't you just love the intrigue here.
I am betting on Cytodyn. Now, will PourhouZin spill some beans in this plea arrangement weaseling out of a potential
bad outcome? Of course, but they will probably make it look good for public consumption. We will never know what is going
down behind the scene. That much we can bank on. Yes, bet prepaid Sidley is all ears and eyes about now. We may be voting
her a bonus one day in the not too distant future.
$CYDY$
LOL, Elfie the FDA agrees and assisted in the protocol hold lifting.
Catch up Elfie Come Lately.
Say, how about the hefty investor list .... any other stock in the OTC with such clout?
Wonder why? Any clue Clouseau?
$CYDY$ Dr. Jay and the HIV boys about to strike up the band.
The thousands of investors are not wrong. Bashers have the game tweeked in their favor only because the SEC has shown
it is not serious about Short loopholes that allow for off the books shorts that originate back to the beastly BIS. This is how they
profit and protect their holdings in Big Pharma at the same time. Down the line pigeons and elves congregate at the pig trough
following their marching orders.
Say, did you glance over the slope line that has lots of big spikes? Some nice profits were made along that route. Better grab some.
We are on the brink of the next spike. Why? Leronlimab lives on and now in better hands than ever.
Buying on the dips. Did that a few days ago again. Nice very nice. We are growing and greening up. Time for you pigeons to take a starter.
Oh, you are secretly long! Well, come out of the closet and get on board the wagon.
$CYDY$ Way to go Dr Jay
the latest PR stated this was coming soon and that it is a small manufacturing concern to handle some domestic demand and for prototyping.
Could well be other new accounts are on slate. I'll take it. It's something better than yesterday. Now what about tomorrow? At least we are moving in the right direction.
You are the master at lying straight out. Have you no shame?
Which company has no product?
You are the master of spin and deception.
You are also the master of no DD.
So I believe strongly in leronlimab as thousands of others do too.
Guess we are all wrong. Where we are wrong is responding to your lies.
Empty out those boots and get to researching leronlimab. Would be a good place to start a real investigation.
$CYDY$ 2024 Leronlimab, making so much fuss. Wonder why?
I feel there would be a really good chance for a partnership or collaboration for Alz.
or for T-NBC. Now that hold is lifted we should see some activity resuming for HIV
7. HIV Gene Therapy Clinical Trials Based on In Vivo Delivery
Studies employing the in vivo approach in HIV are mainly at the pre-clinical stage. In vivo approaches involve the introduction of the gene therapy product directly to the patient using either viral vectors like adenoviral vectors, adeno-associated virus vectors or non-integrating lentiviral vectors, or through non-viral methods like nanoparticles. In vivo methods may not provide a long-lasting cure, because there is no stable integration of the transgene with the host’s genetic material, and the delivery to specific cells needs to be optimised to reduce the chances of off-target effects. Gene editing through recombinase or nuclease systems [61], or silencing mechanisms using RNA interference or possibly CRISPR-interference, could use the in vivo approach.
Current clinical trials include a study that used leronlimab, an anti-CCR5 humanized IgG4 antibody that competitively inhibits HIV env attachment to CCR5 by binding to the same attachment site as CCR5 (the extracellular loop-2 and N-terminus domains). This agent was administered subcutaneously, and the group is currently working on using a synthetic AAV vector for delivery. Several versions of this study—NCT00642707, NCT02175680, NCT02355184, NCT02483078, NCT02990858, NCT03902522, NCT02859961 and NCT05271370—demonstrated the safety and efficacy of the product, with patients experiencing mostly mild side effects and efficacy being observed at higher doses of 525 mg and 700 mg [221].
Advances in HIV Gene Therapy
by Rose Kitawi 1, Scott Ledger 1, Anthony D. Kelleher 1,2,3 and Chantelle L. Ahlenstiel 1,3,* [ORCID]
1
Kirby Institute, University of New South Wales, Kensington, NSW 2052, Australia
2
St. Vincent’s Hospital, Darlinghurst, NSW 2010, Australia
3
UNSW RNA Institute, University of New South Wales, Kensington, NSW 2052, Australia
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2024, 25(5), 2771; https://doi.org/10.3390/ijms25052771
Submission received: 2 November 2023 / Revised: 20 February 2024 / Accepted: 20 February 2024 / Published: 28 February 2024
(This article belongs to the Special Issue Advances in Gene and Cell Therapy 2.0)
Abstract
Early gene therapy studies held great promise for the cure of heritable diseases, but the occurrence of various genotoxic events led to a pause in clinical trials and a more guarded approach to progress. Recent advances in genetic engineering technologies have reignited interest, leading to the approval of the first gene therapy product targeting genetic mutations in 2017. Gene therapy (GT) can be delivered either in vivo or ex vivo. An ex vivo approach to gene therapy is advantageous, as it allows for the characterization of the gene-modified cells and the selection of desired properties before patient administration. Autologous cells can also be used during this process which eliminates the possibility of immune rejection. This review highlights the various stages of ex vivo gene therapy, current research developments that have increased the efficiency and safety of this process, and a comprehensive summary of Human Immunodeficiency Virus (HIV) gene therapy studies, the majority of which have employed the ex vivo approach.
You have been shown already a million times but fail to see.
If you like a definition of absurdity and misinformation look no further than in the mirror.
$CYDY$ 2024
And there's the difference between you and reality. There is not an update as of yet as far as I know.
Most likely they are negotiating a plea.
What do you think? I venture to say, you, the imminent investigator has an inside scoop.
Right? Give us your update on the case Inspector Clouseau
$CYDY$ 2024
Great to hear you are disease free. So do you support Right To Try?
I know nothing of the proceeding at this point. I doubt we hear anything for a week at least. Maybe someone else has heard something.
Hard to say what exactly is the case here. Social media has it's share of posters who for various reasons wish to cast doubt about new products, especially the competition.
Could the lack of shipped product be from an underestimating the initial demand? It takes a bit of patience for a new product like this. Imagine trying to fix a bug or make improvements...can take some time before all ahead go on the production that also may need adjusting. So as things are developing I cut Morvano a little slack here early on. It is impossible to know everything that may occur that requires adjustment with the introduction of a new product and compounded in today's world of fast changing tech.
thanks. and if that is in fact what is happening ..not good. Movano will figure that out.
Regardless, it does not take away from the expansion of liquid metal due to Movano
notoriety and of course Evie rings are still being sold. Growing pains!
I doubt we hear anything for a little bit. The boys are busy copping a plea I would imagine.
As I see it, there are too many loose ends that could damage some reputations that don't
need more damage just now.
"Plea Agreements: Please be aware that many criminal cases are resolved by plea agreement between the Department of Justice and the defendant. You should also know that it is not unusual for a defendant to seek to negotiate a plea agreement shortly before trial is scheduled to begin. Plea agreements can be made at any time and as late as the morning of trial, leaving little or no opportunity to provide notice to you of the date and time of the plea hearing. If the court schedules a plea hearing in this case, we will use our best efforts to notify you of available information as soon as practicable. If you want to inform the prosecutor of your views regarding potential plea agreements, or any other aspect of the case, please contact the prosecutor assigned to this case or call the Victim Assistance Line toll-free at (888) 549-3945 or email us at victimassistance.fraud@usdoj.gov."
Kind of lonely around here. So lets kick this and see if there is any movement.
Sell off ....to me...looks like coming. Uncertainty about Tik Tok, congress, Biden.
Me? I don't think Tik Tok will be booted while current admin is in power. It is too
powerful a voice for the current regime with an election right around the corner. IMO
Will you push for renewed Right To Try? Leronlimab just might help. Worth a try? Seems extraordinarily safe.
$CYDY$ 2024
Wrong again as usual. NO claim just fact. And anyone can tell you don't read too closely or prefer to insert your own interpretations.
The guy was not defended. Can't you tell that? Come now elfie. Time to get real and post like an honest person. You can do it.
$CYDY$ 2024
Ramadan partaking I believe .... no, not him he converted, rather Kazaam, praying intently for salvation from Federal court judge.
Nothing I hope. Nothing inferred as such.
Learn about the company. That is step one in understanding.
Do learn.
So when this investigation started naturally the company will turn over requested documents. Shouldn't the FDA be doing the same?????
Why is the FDA stalling? Doesn't look good for them to do that. What could they be hiding? Perhaps some interesting 13Dudes are wanting
this to be put to rest asap. [Go Sidley gather the data.] Even 13Ddudes will have to be assumed innocent until proven guilty. Boo hoo, that's the way it is supposed to work anyway unless one waved a flag on the wrong day at the wrong place a few years back when leronlimab was making headlines... yes, about that time. Nada coulda shoulda beena hero. How will it end up. IMO, we get the whitewashed version in the end.
So even were CytoDyn being "investigated" the Fed suit is not against CytoDyn... vs Nader and Kareem. The internal documents may
show or may not show others involved yet to be cited. Let the chips fall. Like any good investigator, leave no rock unturned, and proceed to
trial with facts because opinions and half-assed research doesn't get a conviction. Even then the facts may never make it to the table.
would we be going overseas? India or land of the rising sun?
sounds cool to me,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9510552/
And another thing. Only shorties and paid bashers call a long who believes in a company and writes why is termed a pumper. Why is that?
They follow the rules of the short stumpers who pay them and give short advice. Always a straggler or two joins in... basher crowd borders on the retard level ....what is sad is they are killing the cow that gave them a job.
No idiot. I never sell all my shares I accumulate super cheap. I sell enough to buy some weekend beer at the beach and sometimes invest in others but always hold back enough to buy more when the paid bashers get overactive... you can always see it coming.. then load up on more cheapies. Every now and then the stock takes off super high and I start the process over. But get this, I never sell out completely when the fundamentals are strong. The fundamentals here in NBRI are held within the earth.... a really safe bank although a bit cloudy at times thanks to the green new weenies who inadvertently have created a whole new carbon capture market.... which we investors here in NBRI will be in a position to profit from as well. You got to love it FlungPoo.
$NBRI$
Looks also like they tweeked the casting formula to expand better to suit the expanding/contracting of the female digits. The ring also won many awards which of course gathered lots of attention in this rising female health industry. I would assume sales will increase.
No sir, and no peter and sin huevos.
Smarter yes, but I wouldn't go out on the limb so boldly and claim "significant". Trending, ok, you got it.
Laughing
$CYDY$ 2024
As soon as you leave it will stop but be sure and take the other paid bashers with you, then I guarantee the idiotic back and forth will cease. Post that occurrence, we will have a genuine dialogue of the pros and cons.
$CYDY$
but you are the joke.
did u get the punch line?
but not near as stupid as you professor.
Numbers don't lie.
$CYDY$
https://rumble.com/v4jgfj8-the-big-pharma-vaccine-swindle-that-has-been-going-on-long-before-covid-del.html
A must listen for medical personnel especially. All others enter at own risk of .... having eyes opened WIDER.
What part do you refute if any? Be specific.
Smack Down on autism and vaxx in general. A video interview to be bookmarked!
$CYDY$ 2024
Remember, long covid has not been ruled out.... per Dr. J.
"Debunked" LMAO. So why will they not appear in a public debate with the authors?
And what is Qonspiracy?
so watch the last one, the Tucker interview just posted. Yes, try as an investigator or
science researcher to listen, take notes, and see how things turn out over time.
It is undisputed after near 4 years that the jabs don't work as promoted. They do much more harm than good. Data was hidden and changed. Go to congressional testimonies. Natural immunity is way more
preferable should one care about their health. Even Fauci and the CDC have admitted it
and the Lancet had to issue apologies. Conspiracy? Yes, the bat did it ... lol, too bad the congress got a hold of Fauci's emails attempts to cover up the source and also the gain of function research in China they were funding.
Even the Dept of Energy has recently revealed the source of the "bat" was in fact lab derived. However, a consensus from the government getting news attention is for some reason yet to be covered beyond a snippet. So why don't they interview the bat lady who lead the work in the China Lab who gave an interview revealing it? Ah heck, what did she know. Let's brush over the biggest scam in history.