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Burnttoast, I condensed and modified your post for a few relatives that are also investors.
HemoDefend
HemoDefend is Closer to Commercialization with a New $3 million, 3-Year NHLBI Award. This Award, was announced in for CTSO in August. This will be used to fund a pivotal FDA clinical trial,and anticipate that that study will begin in Q1 2019.
The potential market for HemoDefend could be enormous. An estimated 80M -100M blood donations happen each year worldwide with each donation generating multiple blood transfusion products such as packed red blood cells (pRBCs), platelets, fresh frozen plasma, and cryoprecipitate.
The HemoDefend filter removes contaminants such as antibodies, free hemoglobin, cytokines, and bioactive lipids in packed red blood cells.
HemoDefend’s practical and effective ways to purify contaminated blood and reduce risk of transfusion-related adverse reactions is an objective of the NHLBI Award.
The significance of continued development of HemoDefend should not be underestimated. When that happens, it should be a wake-up call for investors value.
Just another buying opportunity.
Article is on page 24
Combination of ECMO and cytokine adsorption therapy for patients
with pneumogenic sepsis and severe respiratory failure
Stefan Fischer1
, Ali Akil1
, Stephan Ziegeler2
, Stephanie Rehers2
, Lars
Richter1
, Michael Semik1 1Department of Thoracic Surgery and Lung
Support, Ibbenbueren General Hospital, Ibbenbueren, Germany;
2
Department of Anesthesiology and Intensive Care Medicine, Ibbenbueren
General Hospital, Ibbenbueren, Germany
Objective: Severe sepsis with systemic inflammation in intensive care
patients is associated with high mortality and morbidity. Often severe
respiratory failure develops, necessitating the application of extracorporeal
respiratory support (ECMO). Here we report the use of a cytokine
adsorber system in combination with ECMO for patients with respiratory
failure due to severe pneumogenic sepsis.
Methods: Between January and April 2018, n = 23 patients with severe
sepsis were supported with a cytokine absorber (CytoSorb®) for cytokine
removal. The data were prospectively documented and retrospectively
analyzed.
Results: N = 10 patients were identified with acute respiratory failure due
to pneumonia with pneumogenic sepsis and underwent combined ECMO
and CytoSorb® therapy. All patients developed severe acute respiratory
distress syndrome (ARDS) and were treated empirically for severe sepsis.
Subsequent analysis of sputum from direct bronchoscopy revealed the
presence of influenza pneumonia in n = 3 patients, fungal pneumonia
in n = 1 patient and bacterial-related pneumonia in n = 6 patients. The
indication for ECMO therapy was the clinical deterioration due to acute
respiratory failure and sepsis-related hemodynamic instability with high
dose infusions of catecholamine (norepinephrine). Peripheral venovenous
(v-v) ECMO was implemented in combination with a Cytosorb®
immunomodulation filter, which was either connected to the ECMO
circuit or added to a hemofiltration circuit. Immediately after CytoSorb®
therapy and also during the further course, a significant reduction of
elevated infection parameters (CRP and leucocytes) was recorded. Most
notably, the initial very high doses of catecholamine could be weaned off
within 12?h and all patients required catecholamine support 24?h after
CytoSorb® initiation. Mean length of postoperative ECMO support was
8 days (7–10 days). The immunomodulation therapy was terminated
after three treatment sessions in all patients after 3 days. There were no
adverse events related to the treatment. All patients were discharged for
further rehabilitation.
Conclusion: The combination of ECMO with an immunomodulatory,
cytokine-adsorbing filter system in patients with respiratory failure due
to pneumogenic sepsis is an effective treatment to prevent escalation
of sepsis. It supports the reversal of septic shock, the rapid weaning off
of high-dose catecholamine infusions as well as the quick resolution of
leucopenia and reduction of CRP levels. Further Studies are needed with
regards to the optimal timing of immunomodulatory therapy and its
impact on ECMO-related inflammation.
Contact person:
Stefan Fischer, MD. MSc. PhD
Director, Department of Thoracic Surgery and Lung Support, Klinikum
Ibbenbueren,
Grosse Strasse 41, 49477 Ibbenbueren, Germany,
Telephone number: 0049-5451-52-2011;
Fax number: 0049-5451-52-5059;
Email: s.fischer@klinikum-ibbenbueren.de
Here is another article.
This article is part of an occasional series on water and hydraulic fracturing by the Texas Tribune and StateImpact Texas.
Call it hydraulic fracturing — without the hydro.
In most hydraulic fracturing operations, several million gallons of water, together with sand and chemicals, get pumped down a hole to blast apart rock that encases oil or gas. But with water increasingly scarce and expensive around Texas, a few companies have begun fracking with propane or other alternative liquids.
“We don’t use any water,” said Eric Tudor, a Houston-based official with GasFrac, a Canadian company that fracks with propane geland butane. “Zip. None.” At a GasFrac operation in South Texas last month, a sticker on one worker’s hard hat showed a red slash through the word H2O.
Water-free fracking still remains an early-stage technology, with potentially higher initial costs than conventional fracking methods. But as lawmakers and oil regulators focus on the large quantity of water used for fracking wells, the concept is getting a closer look.
GasFrac has led the way, bringing its propane fracking operations to Texas, and there is talk of using other substances like carbon dioxide or nitrogen.
“We’ve looked at [propane fracking], and I would say that absolutely our industry is open to all possibilities,” said Michael Dunkel, the director of sustainable development for Pioneer Natural Resources, in testimony last month before a joint hearing of the House Energy Resources and Natural Resources committees.
Waterless fracking is “a viable technology for sure,” said David Yoxtheimer, an extension associate with the Marcellus Center for Outreach & Research at Penn State University. However, he noted, there is a reason that companies use water, namely that it is “virtually incompressible” and thus is very effective in bringing pressure against, and ultimately breaking up, rock.
Currently there are no special rules on fracking with propane or other nonwater liquids in Texas, according to Christi Craddick, one of three members of the Railroad Commission of Texas, which regulates the oil and gas industry. The technology is “exciting” but still rare, she said, and no rule changes are on the horizon.
“We’ll see as the technology evolves if our rules need to evolve,” Craddick said last week in an interview.
Tudor, of GasFrac, said his company began working in Texas in 2010, after fracking its first well in Canada in 2008. It has done roughly 100 fracks in Texas so far, he estimated. (Some wells get fracked multiple times.) Much of the work has been in South Texas. A recent job bored into the San Miguel formation, which is a relatively shallow formation in the vicinity of the Eagle Ford Shale. But GasFrac has also done “a couple of prototype fracks” in West Texas, he said.
“We’re just getting started,” Tudor said.
Academics see a number of challenges associated with propane fracking, which few if any companies are experienting with in Texas, apart from GasFrac. First, according to Yoxtheimer, “you’ve got to truck in a lot of propane,” which can be expensive. He also said the propane “works less effectively in deeper formations where you need to build up more pressure.”
Tudor disagrees that these issues pose problems. He pointed out that the virtually all the propane — which is a byproduct of natural gas processing and oil refining — gets reused. Supplies of propane come from Corpus Christi, he said, and the fuel is “easily available” in South Texas. “We won’t cause any shortages,” he said.
That is an implicit contrast with the considerable water needs of conventional fracking, which already accounts for a double-digit percentage of water use in some rural Texas counties. The water leftover from fracking operations typically does not get reused. Instead, it gets discarded into a disposal well. (The Texas Railroad Commission on Tuesday approved rules to make it easier for companies to recycle water.)
Tudor also said that his company had fracked at depths well over 10,000 feet.
An advantage of propane fracks, said Yoxtheimer, is that they avoid the damage to the oil and gas-producing formation that water can cause.
“If you’re using water, the water can actually block off or at least impede the flow of hydrocarbons,” he said.
Tudor agreed, saying that his company could recover a higher percentage of the oil or gas with propane than with a traditional water frack job. It was this increased production, rather than the reduced use of water, that enticed GasFrac’s customers, he said.
David Burnett, research coordinator at the Department of Petroleum Engineering at Texas A&M University, said that more study is needed. Evidence that the wells fracked with propane are more productive is “sort of anecdotal data,” he said.
As for the risks of handling flammable material like propane, “Our industry is used to handling high-pressure gas and pumping flammable liquids,” Burnett said. “It’s not an issue if the equipment is designed properly.” The risks, he added, are “no more worrisome than a propane tank on the edge of town.”
Tudor said that his company had done 2,000 or more fracks by now, with only one “minor incident in Canada” in which a worker got blisters while some equipment was being shut off. Any leaks, Tuder said, can be “quarantine[d], and “we’re always hooked up to a flare” that can release the gas if needed. The company uses thermal cameras to monitor “hot areas” remotely.
As GasFrac’s technology spreads, other companies are also trying to use less water. In testimony last month before the joint hearing of the House Natural Resources and House Energy Resources committees, Glenn Gesoff, an official with BP who also chairs the water committee of the Texas Oil and Gas Association, told lawmakers that there were “a number of tests going on” in waterless fracking and fracking that uses significantly less water. In addition to propane, he said, work is ongoing with carbon dioxide and nitrogen.
“They’re in the development phase,” Gesoff said. “There are some safety concerns.”
Marathon Oil has begun using a new formula, which it describes as a “guar mix commonly used in ice cream and other food products,” to reduce its water use. Guar is a small bean that can thicken water, and the thicker fluid can carry the sand and other elements “while simultaneously using less water,” said Lee Warren, a Marathon Oil spokesman, in
An article on the Eagle Ford Reservoir, where GSFVF is becoming a player, they state:
Onshore, the potential is even greater with more than 60 billion untapped barrels, according to a Pemex presentation last month.
Some of the potential shale production sits across the border from Texas’s prolific Eagle Ford formation. The most resource-rich area studied so far is around the city of Tampico, a coastal city about 300 miles (480 kilometers) south of the bottom tip of the Texas border.
“I can’t tell you the amount of banks and investment funds coming from the U.S. and Europe that have been talking to us and are trying to have an expectation of what’s going to happen with the energy reform,” Prado said. “All those guys are going to be in Mexico next year in various forms trying to seek new opportunities.”
I believe that GSFVF is finally nearing a nice payoff.
I am afraid we have already been caught with our pants down and Willy had his way with us.
At this point, I am trying to run away with my pants at my knees, and get away with a little dignity.
Even bad people can be successful. I have certainly run into a number of these in the business world.
At this point in Willy's career, he should not be able to find very many more suckers like us. He needs a home run, just to gain some street credability.
He may be a rat, but he is our rat, and if this ship goes down, he goes down with us.
I'm with you Rocky. Selling now would net me nothing but a good tax write off.
I have heard the Chinese were slow in negotiating, but even I don't think they could be this slow.
Must be somebody else ringing the doorbell
Fighting over a pennant/ no pennant to determine the direction of SRSR movement is the equivalent of fighting over a turd.
This is a story stock, and the only thing that will move it up is good news.
Probably a good thing. We know there are some serious bucks there.
I thought you would know.
You are right, but I have seen new investor groups place a person they are associated with on the BOD, just to keep an eye on their money.
Of course, I have no idea if this is the case here or whether or not Ben Ward is closely associated with big money.
Has there ever been any talk about MMTE partnering with SQM/
Just curious.
A while back there was talk about WL merging us with LEXG. LEXG is now talking about merging with GDCI.
The GDCI baords states:
Over the last six months GDGI has established relationships with strategic partners in the Americas, Europe, and the Middle East, including Argentina, Bolivia, Brazil, Germany, Saudi Arabia, the United Arab Emirates, the United States of America and Venezuela. Within these countries, targeted industries include desalination, mineral extraction/tailings (copper, lithium, and gold), natural gas hydraulic fracturing, and oil (thinning and refining).
Maybe this is the Grand Plan for Chile minerals?
Great info Superman. It looks like niobium could be a vital part of our daily lives in the not too distant future.
Combine this with the 14000 MPH Maglev, with its niobium-titanium alloy magnets, and we will be rolling in cash from niobium sales?
I use Etrade with no complaints. I buy and sell, don't trade much, if any.
I was referring to Web's.
El Toro means the bull, which is how I feel about SRSR.
Looking back at past reports, they had the same statement in each of them.
I was just curious as to why webpence had highlighted it in his post this time. I was really hoping he was inferring that the results could be better than in the past. Just hoping!
Web, the words that you put in italics are standard boilerplate in any safe harbor statement.
Did you intend to infer anything other than buyer beware?
Great article!
A synthesized form of niobium oxide could lead to high-performance supercapacitors
(Nanowerk News) Taking a significant step toward improving the power delivery of systems ranging from urban electrical grids to regenerative braking in hybrid vehicles, researchers at the UCLA Henry Samueli School of Engineering and Applied Science have synthesized a material that shows high capability for both the rapid storage and release of energy.
In a paper published in the April 14 issue of the journal Nature Materials ("High-rate electrochemical energy storage through Li+ intercalation pseudocapacitance"), a team led by professor of materials science and engineering Bruce Dunn defines the characteristics of a synthesized form of niobium oxide with a great facility for storing energy. The material would be used in a "supercapacitor," a device that combines the high storage capacity of lithium ion batteries and the rapid energy-delivery ability of common capacitors.
nobium oxide
Illustration of form of nobium oxide synthesized by UCLA researchers.
UCLA researchers said the development could lead to extremely rapid charging of devices, ranging in applications from mobile electronics to industrial equipment. For example, supercapacitors are currently used in energy-capture systems that help power loading cranes at ports, reducing the use of hydrocarbon fuels such as diesel.
"With this work, we are blurring the lines between what is a battery and what is a supercapacitor," said Veronica Augustyn, a graduate student in materials science at UCLA and lead author of the paper. "The discovery takes the disadvantages of capacitors and the disadvantages of batteries and does away with them."
Batteries effectively store energy but do not deliver power efficiently because the charged carriers, or ions, move slowly through the solid battery material. Capacitors, which store energy at the surface of a material, generally have low storage capabilities.
Researchers on Dunn's team synthesized a type of niobium oxide that demonstrates substantial storage capacity through "intercalation pseudocapacitance," in which ions are deposited into the bulk of the niobium oxide in the same way grains of sand can be deposited between pebbles.
As a result, electrodes as much as 40 microns thick — about the same width as many commercial battery components — can quickly store and deliver energy on the same time scales as electrodes more than 100 times thinner.
Dunn emphasizes that although the electrodes are an important first step, "further engineering at the nanoscale and beyond will be necessary to achieve practical devices with high energy density that can charge in under a minute.
Read more: http://www.nanowerk.com/news2/newsid=29995.php#ixzz2Xk9M3c2u
Thanks Supermegadope. This is great info.
dmbao, That is the price I remember also.
Another point that esi1 fails to look at is
that SOE is an end-user, so his arguments
about monopolies and pricing would be irrelevant,
if we do a deal with the SOE.
That is what I was thinking. Niobium has been used for too long for this process to be secret.
I guess you could compare it to McDonalds "secret sauce" or the coke formula. Who cares?
Boy, that is for sure. As far as I can tell, he has not wasted one dime of our money.
The rocks will still be in Canada.
Add 47,000,000 for me.
Nitwit, I forgot I had a sell in at .038 and it went through also.
That's ok I have plenty left, and if it drops back before Sept.30, I will buy more.
Just curious as to why they would not. If price was the problem, did they say at what point they would take it?
Just call 1800etrade1. they will tell you how to do it.
Thanks Web. I got through the first three pages (including the index) and my careful conclusion is that Niobium is the best material.
That is all I need to know.
Most likely, that is the market maker playing with the shares price. If you want to see for sure, but 100 shares and try to make a profit on them.
Nemo, have you looked at Trilliant's volume?
The price means nothing when the volume is 400 shares.
I'm going to name mine Houdini or Jesus.
OOps, forgot my wife is 65. I get so excited when you start talking about those big numbers
I am impressed by this.
Me also, BR.
Dawg,
I believe that a R/S would also be needed in order to move on to a more respectable stock exchange.
What are your thoughts on that?
It all depends on the companies accomplishments or potential. If this is done as a desperate act to save a company with a dismal future, you are correct.
If it is done by a company that has good assets and needs to be recognized on a reputable stock exchange, this can be a good thing.
In the pinkies there are very few good examples of success no matter what the stock format is. I can only hope we are in the process of "catching lightining in a bottle", with WL's help.
Thanks, and may we all achieve our dreams.
Makes sense Daytona. Unfortunaltely most of us thought we saw the MoMo happening a number of times before when the price was a lot higher.
I still believe it will happen, and you probably will be able to catch some as it rockets up. I for one, have all the stock I need to be rich, if and when this happens.
Good luck with your plan. In retrospect you will appear to be a lot smarter than us.
But if you are wrong and a big deal is closed, we will be looking at you in the rear view mirrors of our Bentleys and laughing.
I also agree with you on the R/S. I cannot see the difference between owning millions of shares worth .0004 each or 1,000's of shares worth $4 each.
Be careful. When I tried to open this link, my Kaspersky denied access and stated a Trojan Horse was embedded.